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On World Cancer Research Day, Illumina Highlights the Transformative Power of Genomics – Yahoo Finance

On World Cancer Research Day, two experts share their enthusiasm for the potential of genomic and multiomic data to transform oncology

Northampton, MA --News Direct-- Illumina

Cancer is a devastating disease that is quickly becoming the leading cause of death worldwide. In 2020, there were nearly 10 million cancer deaths around the globe. But with the advent of genomics and a democratized access to specialized data, cancer researchers have been able to make great strides in recent years, and cancer survival rates have increased thanks to advancements from research.

September 24 marks World Cancer Research Day. The initiative aims to promote research in the oncology field and calls on institutions, leaders, and enterprises to increase their efforts and accelerate momentum as they strive to lessen the burden of this heartbreaking disease.

At Memorial Sloan Kettering Cancer Center (MSKCC) in New York City, Assistant Attending Computational Oncologist Elli Papaemmanuil, PhD and her lab utilize Illumina technologies to analyze multiomic data (any combination of DNA, RNA, epigenetics and protein) from thousands of patients to gain actionable insights into cancer. There is so much information embedded in the cancer genome that speaks to a patients risk predisposition, disease state, and the likely response to treatment, says Papaemmanuil. We now have the technologies that allow us to access that information. When thinking about a new problem, reading a paper, or working on a challenging patient, clinicians thought processes now immediately jump to thinking about how they can use the latest technologies to solve a problem. I find this shift incredibly inspiring. It shows that were just at the very beginning of adopting these technologies in a much wider context.

Danny Wells, PhD, is the Senior Vice President of Strategic Research & Scientific Co-Founder of Immunai, and is equally enthusiastic about the power of next-generation sequencing to gain critical insights. Im a true believer in genomicsI think the skys the limit. This technology will become central to every major disease research area.

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His company, also based in New York City, is mapping the bodys immune system using multiomics and AI in order to discover new therapies. Wellss background includes biology and applied mathematics, but today he focuses on immuno-oncology research. For me, there are two really profound differences between working with genomic data in the context of human health compared to the computational work I did in the past. The first thing is that I just love genomic data. Its so incredible that you can take these unbiased approaches. I dont think any other data types give you access to that much information. Secondly, its meaningful to be working on human samples and to know that discoveries youre making can help identify new treatments for patients, new ways to get them the right therapy.

Wells is one example of how advances in sequencing have attracted a range of talent to the field of genomics research. According to Papaemmanuil, the global research community is no longer just trained scientists predominantly studying genomics and data science. Now, individuals that may have diverse backgrounds in cell biology or molecular biology are routinely incorporating technologies that allow the decoding of the cancer genome, methylome, and transcriptome on a daily basis. An important point is that these technologies are not only generating the data, but are also naturally paired with an associated workflow for quality control and data mining after the data generation. The stability of that output is what has effectively enabled and democratized the adoption of these technologies across disciplines. The high quality of the output has enabled very reliable new discoveries for us and for many others.

But there is much more work to be done, and it begins with the researcher. The more comprehensively we interrogate the genome, transcriptome, and methylome, the faster we will be able to develop and validate relevant biomarkers, she says. Once we have exhausted our search space, we will be able to link multiomic data to patient response status and outcomes in all our correlative studies and clinical trials.

To read Illuminas Cancer Research Methods Guide, click here.

To support cancer researchers, visit World Cancer Research Day and use the hashtag #WorldCancerResearchDay on social media.

View additional multimedia and more ESG storytelling from Illumina on 3blmedia.com

View source version on newsdirect.com: https://newsdirect.com/news/on-world-cancer-research-day-illumina-highlights-the-transformative-power-of-genomics-496632398

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An Introduction to Portfolio Optimization in Python – Built In

In investing, portfolio optimization is the task of selecting assets such that the return on investment is maximized while the risk is minimized. For example, an investor may be interested in selecting five stocks from a list of 20 to ensure they make the most money possible. Portfolio optimization methods, applied to private equity, can also help manage and diversify investments in private companies. More recently, with the rise in cryptocurrency, portfolio optimization techniques have been applied to investments in Bitcoin and Ethereum, among others.

In each of these cases, the task of optimizing assets involves balancing the trade-offs between risk and return, where return on a stock is the profits realized after a period of time and risk is the standard deviation in an asset's value.Many of the available methods of portfolio optimization are essentially extensions of diversification methods for assets in investing. The idea here is that having a portfolio of different types of assets is less risky than having ones that are similar.

Finding the right methods for portfolio optimization is an important part of the work done by investment banks and asset management firms. One of the early methods is called mean variance optimization, which was developed by Harry Markowitz and, consequently, is also called the Markowitz Method or the HM method. The method works by assuming investors are risk-averse. Specifically, it selects a set of assets that are least correlated (i.e., different from each other) and that generate the highest returns. This approach means that, given a set of portfolios with the same returns, you will select the portfolio with assets that have the least statistical relationship to one another.

For example, instead of selecting a portfolio of tech company stocks, you should pick a portfolio with stocks across disparate industries. In practice, the mean variance optimization algorithm may select a portfolio containing assets in tech, retail, healthcare and real estate instead of a single industry like tech.Althoughthis is a fundamental approach in modern portfolio theory, it has many limitations such as assuming that historical returns completely reflect future returns.

Additional methods like hierarchical risk parity (HRP) and mean conditional value at risk (mCVAR) address some of the limitations of the mean variance optimization method. Specifically, HRP does not require inverting of a covariance matrix, which is a measure of how stock returns move in the same direction. The mean variance optimization method requires finding the inverse of the covariance matrix, however, which is not always computationally feasible.

Further, the mCVAR method does not make the assumption that mean variance optimization makes, which happens when returns are normally distributed. Since mCVAR doesnt assume normally distributed returns, it is not as sensitive to extreme values like mean variance optimization. This means that if a stock has an anomalous increase in price, mCVAR will be more robust than mean variance optimization and will be better suited for asset allocation. Conversely, mean variance optimization may naively suggest we disproportionately invest most of our resources in an asset that has an anomalous increase in price.

The Python package PyPortfolioOpt provides a wide variety of features that make implementing all these methods straightforward.Here, we will look at how to apply these methods to construct a portfolio of stocks across industries.

More From Sadrach PierreNeed to Perform Financial Data Analysis? Why Python Is Your Best Tool.

We will pull stock price data using the Pandas-Datareader library. You can easily install the library using pip in a terminal command line:

Next, lets import the data reading in a new Python script:

We should pull stocks from a few different industries, so well gather price data in healthcare, tech, retail and finance. We will pull three stocks for each industry.Lets start by pulling a few stocks in healthcare. We will pull two years of stock price data for Moderna, Pfizer and Johnson & Johnson.

First, lets import Pandas and relax the display limits on rows and columns:

Next, lets import the datetime module and define start and end dates:

Now we have everything we need to pull stock prices. Lets get data for Moderna (MRNA):

Lets wrap this logic in a function that we can easily reuse since we will be pulling several stocks:

Now, lets pull for Pfizer (PFE) and Johnson & Johnson (JNJ):

Lets define another function that takes a list of stocks and generate a single data frame of stock prices for each stock:

Now, lets pull stocks for the remaining industries:

Healthcare: Moderna (MRNA), Pfizer (PFE), Johnson & Johnson (JNJ)

Tech: Google (GOOGL), Facebook (FB), Apple (AAPL)

Retail: Costco (COST), Walmart (WMT), Kroger Co (KR)

Finance: JPMorgan Chase & Co (JPM), Bank of America (BAC), HSBC Holding (HSBC)

We now have a single dataframe of returns for our stocks. Lets write this dataframe to a csv so we can easily read in the data without repeatedly having to pull it using the Pandas-Datareader.

Now, lets read in our csv:

Now we are ready to implement the mean variance optimization method to construct our portfolio. Lets start by installing the PyPortfolioOpt library:

Now, lets calculate the covariance matrix and store the calculated returns in variables S and mu, respectively:

Next, lets import the EfficientFrontier module and calculate the weights. Here, we will use the max Sharpe statistic. The Sharpe ratio is the ratio between returns and risk. The lower the risk and the higher the returns, the higher the Sharpe ratio. The algorithm looks for the maximum Sharpe ratio, which translates to the portfolio with the highest return and lowest risk. Ultimately, the higher the Sharpe ratio, the better the performance of the portfolio.

We can also display portfolio performance:

Finally, lets convert the weights into actual allocations values (i.e., how many of each stock to buy). For our allocation, lets consider an investment amount of $100,000:

Our algorithm says we should invest in 112 shares of MRNA, 10 shares of GOOGL, 113 shares of AAPL and 114 shares of KR.

We see that our portfolio performs with an expected annual return of 225 percent. This performance is due to the rapid growth of Moderna during the pandemic. Further, the Sharpe ratio value of 5.02 indicates that the portfolio optimization algorithm performs well with our current data. Of course, this return is inflated and is not likely to hold up in the future.

Mean variance optimization doesnt perform very well since it makes many simplifying assumptions, such as returns being normally distributed and the need for an invertible covariance matrix. Fortunately, methods like HRP and mCVAR address these limitations.

The HRP method works by finding subclusters of similar assets based on returns and constructing a hierarchy from these clusters to generate weights for each asset.

Lets start by importing the HRPOpt method from Pypfopt:

We then need to calculate the returns:

Then run the optimization algorithm to get the weights:

We can now print the performance of the portfolio and the weights:

We see that we have an expected annual return of 24.5 percent, which is significantly less than the inflated 225 percent we achieved with mean variance optimization. We also see a diminished Sharpe ratio of 1.12. This result is much more reasonable and more likely to hold up in the future since HRP is not as sensitive to outliers as mean variance optimization is.

Finally, lets calculate the discrete allocation using our weights:

We see that our algorithm suggests we invest heavily into Kroger (KR), HSBC, Johnson & Johnson (JNJ) and Pfizer (PFE) and not, as the previous model did, so much into Moderna (MRNA). Further, while the performance decreased, we can be more confident that this model will perform just as well when we refresh our data. This is because HRP is more robust to theanomalous increase in Moderna stock prices.

The mCVAR is another popular alternative to mean variance optimization. It works by measuring the worst-case scenarios for each asset in the portfolio, which is represented here by losing the most money. The worst-case loss for each asset is then used to calculate weights to be used for allocation for each asset.

Lets import the EEfficicientCVAR method:

Calculate the weights and get the performance:

Next, get the discrete allocation:

We see that this algorithm suggests we invest heavily into JP Morgan Chase (JPM) and also buy a single share each of Moderna (MRNA) and Johnson & Johnson (JNJ). Also we see that the expected return is 15.5 percent. As with HRP, this result is much more reasonable than the inflated 225 percentreturns given by mean variance optimizationsince it is not as sensitive to the anomalous behaviour of the Moderna stock price.

The code from this post is available on GitHub.

More in FinanceIs Your Startup Fundraising in 2021? This Is Your Time.

Although we only considered healthcare, tech, retail and finance, the methods we discussed can easily be modified to consider additional industries. For example, maybe you are more interested in constructing a portfolio of companies in the energy, real estate and materials industry. An example of this sort of portfolio could be made up of stocks such as Exxonmobil (XOM), DuPont (DD), and American Tower (AMT). I encourage you to play around with different sectors in constructing your portfolio.

What we discussed provides a solid foundation for those interested in portfolio optimization methods in Python. Having a knowledge of both the methods and the tools available for portfolio optimization can allow quants and data scientists to run quicker experiments for optimizing investment portfolio.

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Life sciences use of digital twins mirrors its application in other industries – MedCity News

Digital twins, virtual representations of objects or processes in the real world, are increasingly finding use in life sciences applications, but the example that many people use to explain the concept is an old one that comes from a different industry entirely. More than a half century ago, the astronauts of Apollo 13 were guided home with the help of simulations conducted here on Earth.

Conditions caused by a potentially catastrophic failure were replicated in simulators erected at NASA, said Andy Greenberg, managing director and North America digital health lead, life sciences, at Accenture. By testing 15 different simulations, NASA was able to find ways to work around problems the astronauts encountered. The test scenarios were analog, not digital. But the concept of conducting tests of equipment or a process while that process is already underway is representative of one of the ways digital twins are employed in the life sciences.

When its at its most powerful, it allows us to ask what if questions in a ways that we could never imagine before, Greenberg said.

Greenberg moderated the panel On Demand: The Role of Digital Twins in Life Sciences, during MedCity News INVEST Digital Health conference this week. He was joined by speakers from GlaxoSmithKline, Dassault Systmes, IDBS, and Unlearn.AI.

GlaxoSmithKlines use of digital twins evokes the simulations that NASA conducted with Apollo 13, according to Sandrine Dessoy, the companys digital innovation lead. In vaccines production, GSK runs simulations to represent whats happening in cell culture or in the purification step that follow. Those models are linked with the actual process in real time. Data from the real process are fed into the simulator, a digital twin that reproduces what can happen in bacteria, a bioreactor, or purification equipment. These simulations give insight into whats happening with the quality of vaccine produced at that moment, so that technicians can see if the product lines up with vaccine specifications, Dessoy said.

Dessoy added that digital twins will play a key role in the development and production of new Covid-19 products. The technology can be used for designing drugs and vaccines; in the case of vaccines, the technology can help scientists select the best antigen to use, she said. Process development can also be done virtually.

If you have to run a cell culture experiment, [it] can take three weeks. In a computer it will take you a few minutes, she said. So, you will drastically reduce the time to develop your process.

At Dassault Systmes, digital twin research led to the development of a human heart that can test medical products virtually before they are tested in patients. Steven Levine, the companys senior director of virtual human modeling, said that this virtual capability is replacing animal testing. The technology has found its fastest adoption in medical devices. Devices that have been validated with the virtual heart are now going through regulatory review. The heart model is also finding applications in clinical practice, allowing surgeons to run simulations of procedures for challenging pediatric cases.

They can practice the surgery beforehand, five, 10 times, predict the outcome, the same way the Apollo scientists did, Levine said. We can do that quickly in the virtual world and then perform those surgeries. And thats happening, and already lives have been saved.

In drug research, digital twin technology is finding use a way of speeding up clinical trials. Unlearn.AI develops digital twins of individuals who are enrolled in drug studies. Charles Fisher, the startups founder and CEO, said the technology allows the company to ask what would happen to a person if he or she were randomly assigned to receive an existing comparative treatment. Predictions from these twins allow clinical trials to run more quickly, with fewer patients needing to be assigned to receive a placebo. The companys technology is currently being used in studies of experimental Alzheimers disease drugs.

We can help people run clinical trials that have the same degree of rigor and evidence, but require 25 percent or so fewer patients, Fisher said. Thats a dramatic reduction in the timeline and costs of the clinical trials.

Alberto Pascual, director of data science and analytics at IDBS, said that the life sciences industry is looking for ways to improve efficiency and reduce costs. The company, part of global technology giant Danaher, develops software used in drug discovery and development. Each step of the drug development process produces copious amounts of data that must be managed. Those data can be used to create modelsdigital twins.

IDBS was doing digital twin technology before the companys computer scientists had heard of the term, Pascual said. Much of its use today is focused on individual instruments that scientists want to replicate with a twin. Looking ahead, he envisions broader simulations, perhaps entire labs.

I can foresee a few years from now, a full factory or a manufacturing plant fully automated with multiple twins, Pascual said. Then you can simulate the full lab.

Photo by Flickr user sumo4fun via a Creative Commons license

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Altcoins Surge as Crypto Market Regains Steam – CoinDesk

  1. Altcoins Surge as Crypto Market Regains Steam  CoinDesk
  2. Altcoins Rally As The Cryptocurrency Market Recovers  Yahoo Finance
  3. Avalanche Price Predictions: How High Can an Altcoin Rally Take the AVAX Crypto?  InvestorPlace
  4. Altcoins Surge As Crypto Makes A Recovery  Bankless Times
  5. As Bitcoin falters, here is the altcoin analysts are dubbing the next Solana  Crypto News Flash
  6. View Full Coverage on Google News

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Altcoin roundup: Theres more to DeFi than just providing liquidity – Cointelegraph

The growth of the decentralized finance (DeFi) sector has been a recurrent headline throughout 2021 and to date, hundreds of billions of dollars in crypto assets are locked on protocols across numerous blockchain networks and earning a yield for their holders.

What started off as a simple Ethereum-based swap interface that allowed ERC-20 tokens to be exchanged in a decentralized manner, called Uniswap, has exploded into a vast ecosystem full of decentralized exchanges, yield farms, lending protocols and staking platforms.

As development continues and older protocols become more established, newer projects have emerged to incorporate more pieces from the traditional financial realm into the DeFi arena as digital technology slowly transforms the global financial system.

Heres a look at some ways for users to get involved with DeFi outside of simply staking in liquidity pools or depositing to a lending protocol.

Cryptocurrency derivatives exchanges have long been a target for regulators, and once defiant exchanges like BitMEX and Binance have found themselves bending to the will of the law and modifying their operating practices as they seek a more legitimate standing.

This has furthered the necessity for crypto traders to have a decentralized option and led to the creation of protocols like dYdX and Hegic, which offer similar services without the target that is a centralized structure for regulators to come after.

DYdX is a non-custodial perpetuals trading platform built on a layer-two protocol that operates on the Ethereum network and offers users access to up to ten times leverage on futures contracts for more than twenty cryptocurrencies.

Hegic is an on-chain options trading protocol that utilizes hedge contracts and liquidity pools to offer options contracts that last up to 90 days and can payout in Ether (ETH), Wrapped Bitcoin (WBTC) or USD Coin (USDC).

Both of these platforms offer users access to these advanced trading products without the need to divulge their identities, as is required on the centralized counterparts.

One topic that is increasingly popping up more in financial discussions is the concept of how to create a decentralized reserve currency that is free of the control of any government or centralized financial institution.

Olympus aims to address this issue through a decentralized autonomous organization (DAO) platform which offers staking and various bond offerings including the ability to bond Ether, MakerDAO (DAI), Liquidity USD (LUSD) and Frax (FRAX).

The bonding process on Olympus is basically a cross between a fixed income product, a futures contract and an option. Bonders are provided with a quote outlining terms for a trade at a future date and include a predetermined amount of the protocols native OHM token that the bonder will receive once the vesting period is complete.

Funds that are raised by bond offerings go into the Olympus treasury as collateral to back the OHM tokens that were minted, helping to provide the underlying value behind the OHM token which allows it to be used as a reserve currency or medium of exchange.

The only other projects that have a treasury that provides the underlying value for each token are stablecoins, but as the name implies their price is fixed whereas the price of OHM can increase, offering a new avenue of yield for users.

Once bonding is complete, users can sell their OHM on the open market or stake them on the Olympus protocol for a current yield of 7,299%.

Related: CFTC renewed: What Bidens new agency picks hold for crypto regulation

Another way crypto holders can put their assets to work while also helping the cryptocurrency ecosystem expand is through participating in the parachain auctions in the Polkadot and Kusama ecosystems through a process known as a crowd loan.

In the auction process, different projects vie for one of the limited parachain slots that connect the project directly to the main Kusma or Polkadot network, facilitating the interconnection of all parachains in the ecosystem.

With crowdloans, users who hold the native KSM and DOT tokens can contribute them towards the pool that a project uses to secure a parachain slot, and they will have their tokens returned after a specified lock-up or bonding period that can last for up to one year.

In exchange for their contribution and inability to earn staking rewards for the period that the tokens are locked up, users receive a specified number of tokens for the new protocol which can then be used in the ecosystem or sold on the market.

This approach offers a less risky yield opportunity for token holders, as all principal contributions are locked in a smart contract and returned after the stipulated lock-up period. And by the nature of the parachain auction process, there have been well-developed projects with larger communities that have secured parachain slots, increasing the chance that their tokens will maintain or increase in value as long development for the protocols stays active.

Aside from the threat of regulation, the DeFi ecosystem is showing few signs of slowing its integration of the best parts of the traditional financial system and developing innovative protocols that level the playing field for retail investors.

The views and opinions expressed here are solely those of the author and do not necessarily reflect the views of Cointelegraph.com. Every investment and trading move involves risk, you should conduct your own research when making a decision.

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Best altcoins to buy: Experts share cryptocurrencies they’re buying – Business Insider

Cryptocurrencies have exploded in popularity over the last several months. Of course, the most popular remains bitcoin.

But some other smaller cryptos are gaining serious steam as well, as the concept of digital currencies continues to seep into the public consciousness.

However, it can be difficult to know which cryptocurrencies to invest in, or whether you should in the first place. There are currently thousands of different types of coins on the market. And some like dogecoin, which was founded as a joke don't appear to be serious. Others, like some built on the Ethereum blockchain, appear to have better use cases.

And overall, there are legitimate concerns over whether the altcoin boom is unsustainable and will soon come crashing down.

Crypto is an esoteric domain its intricacies can be difficult to understand, especially for those new to the space.

To help cut through the noise, Insider has talked to several experts about which altcoins cryptocurrencies other than bitcoin they believe have the best upside. These experts also described the fundamentals and technicals that make these altcoins attractive. Their views are shared in the articles below.

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John Vasquez quit a 12-year banking career to dive into crypto full-time.

He's betting that the massive wealth transfer from baby boomers to their younger heirs will lead to a crypto boom.

Vasquez, known as Coach JV on social media, explained what people should know about crypto before investing and the altcoins he's buying.

Crypto technical analyst Adrian Zduczyk says some altcoins due to outperform bitcoin in a "legendary" way. Zduczyk is the founder and CEO of the Birb Nest, a trading platform. He shared five altcoins with us that he thinks could surge 10-100 times.

Ethereum is the second-biggest cryptocurrency at the moment, sitting behind bitcoin. But it has problems like expensive transaction fees. Matthew Sigel, head of digital asset research at VanEck, shares three altcoins to rival ether.

The looming debt crisis of Chinese real estate developer Evergrande sent shockwaves through global equity markets in September and crypto was not spared.

Given the recent sell-offs, Goodman said he was keeping his money on the sidelines in the crypto space until prices appear to be in an uptrend again.

He shared four projects he thinks can do well in the longer-term.

Ethereum's major upgrade in early Augustled to a9.6% intraday price spike, and investors haven't yet sold the positive news. That's one reason why David Gokhshtein is bullish. He also told us his theses for six smaller altcoins he owns.

Various cryptos tumbled on Tuesday September 7 as El Salvador officially adopted bitcoin as legal tender. By the following morning, more than $3.25 billion in crypto positions had been liquidated over 24 hours, affecting more than 300,000 traders, according toBybit. We asked experts what was driving the sell-off, and where they recommended buying dips.

When dogecoin rose over 12,000% to $0.68 earlier this year, it shocked the investing community. It has since cooled off, though its price has picked up in recent weeks. It now sits around $.027. What will it do next? Chainalysis chief economist Philip Gradwell broke down why he think it will go to $1.

Insider recently hosted a live webcast featuring two crypto experts. They broke down their views on everything from the recent slump to the possibility of regulation.

Lyn Alden says most altcoins are "smoke and mirrors." But there are at least two with interesting technologies that are worth watching.

As some altcoins have shown, there is potential for huge appreciation in crypto outside of bitcoin. David Gokhshtein is one investor that's looking to take advantage of these opportunities. He shared two altcoins he's bullish on.

The broader crypto space just went through a rough patch after huge gains earlier this year. Like any asset class, it has its bull and bear markets. When crypto bear markets do come, crypto influencers Mack Lorden and Lucas Dimos told us that six altcoins in particular help them hedge losses.

Many altcoins are built on top of the Ethereum blockchain. Aya Kantorovich, the head of institutional coverage at crypto exchange FalconX, shared nine coins built on top of the ethereum blockchain that she thinks have solid use cases.

"I personally always like coins with application," Kantorovich said.

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This Magical Altcoin Project Has Soared 116% This Week, Defying Bitcoin and Crypto Markets – The Daily Hodl

An altcoin powering the crypto project Abracadabra has traders spellbound this week after surging by more than 100%.

Data from CoinGecko shows the price of Spell Token (SPELL), which currently holds a market cap of about $221 million, rose from a 7-day low of $0.00197753 to a high of $0.00428190 this week, which represents an increase of 116%.

The coin has catapulted its way to becoming the 245 largest coin on the market.

Meanwhile, Bitcoin climbed from a 7-day low of $40,554.38 to a high of $48,852.87 this week, marking an increase of 20%.

Abracadabra is a lending platform that allows users to borrow the USD-pegged stablecoin Magic Internet Money (MIM) using interest-bearing tokens as collateral.

MIMs can be traded with other stablecoins including Tether (USDT), Dai (DAI), and USD Coin (USDC).

Users can stake SPELL to obtain sSPELL tokens that will grant them platform voting rights and a claim to fees generated by the protocol.

SPELL soared as Abracadabra announced a partnership with the decentralized reserve currency protocol Olympus (OHM) and officially launched the sSPELL lending market.

The project originally launched on Ethereum and is now also available on both the Avalanche and Fantom ecosystems.

Featured Image: Shutterstock/Julia Ardaran and Salamahin

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Here Are the Top 5 Altcoins for the Remainder of September, According to Crypto Analyst Michal van de Poppe – The Daily Hodl

Widely followed crypto analyst Michal van de Poppe is laying out his top five altcoins to watch for the rest of this month.

In a new strategy session, Van de Poppe starts his list with Cosmos (ATOM), a project dubbed as the internet of blockchains. Though ATOM has already exploded in USD value, the analyst looks at its Bitcoin pair (ATOM/BTC) and posits that the hot altcoin still has room to grow over 170% from current prices of 0.00089 BTC, worth $40.51.

We could be targeting 0.0012 BTC ($54) and 0.0017 BTC ($77). 0.0017 BTC will probably be alongside with ATOM at $100.

Van de Poppes second altcoin is privacy-focused Mina, which he says is primed for a potential 129% rally to $12.00 from its current price of $5.22.

Great strength, beautiful support resistance flip, almost 2x since we have mentioned it earlier this month, and now we are looking for some consolidation before we have some continuation here too

Next targets for MINA if were going to have the continuation of the bull cycle: $8.60 and $12.00 at this stage.

The third altcoin on Van de Poppes radar is decentralized oracle network Chainlink (LINK). The analyst says that while LINK hasnt made much of a move over the last month, he stands by his forecast that the crypto can still potentially surge.

LINK and especially the entire oracle section still has to have some momentum at this point, so I think its still a very interesting cryptocurrency to look at or an investment to look at for a potential swing trade.

The fourth crypto Van de Poppe is looking at is Ethereum scaling solution Harmony (ONE). According to the crypto trader, ONE may have already lost steam after its rally this month, but the altcoin could provide a good entry point in its Bitcoin pair (ONE/BTC) at a couple of key levels.

The interest for me, personally, in Harmony is slightly gone until we hit around 0.000003 BTC ($0.14) or maybe even around 0.0000027 BTC ($0.12). That would probably grant another great entry.

The last altcoin to keep an eye on for the rest of September according to Van de Poppe is proof-of-stake blockchain Tezos (XTZ). The crypto analyst says that XTZ has kicked off a new trend and is providing an entry point in its Bitcoin pair (XTZ/BTC).

So we can be assuming that a new trend has started in which we can be looking at a potential support resistance flip as a potential target zone to take the entry from, which is around 0.00012 BTC ($5.73).

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These Five Altcoins Are About To Go Insane, According to Crypto Trader Aaron Arnold – The Daily Hodl

Crypto trader and YouTube influencer Aaron Arnold is highlighting his top five altcoins as he predicts the crypto markets are about to go insane.

In a new video, Arnold tells his 998,000 YouTube subscribers that hes bullish on decentralized oracle Chainlink.

Chainlink is kind of a blue-chip in what it does. No other oracle crypto like Chainlink is doing it as big as Chainlink LINK looks like its gearing up for a breakout. So Chainlink, yeah, I happen to be bullish as long as were in a bull cycle.

Looking at Polkadot (DOT), Arnold cites a crypto strategist who believes that the interoperable blockchain will follow the footsteps of explosive altcoin Solana (SOL).

This particular analyst is comparing it, saying that DOT could pull a move like Solana. Getting some major Solana vibes from DOT. Its been rejected a few more times, but I think the trajectory (weekly candle close), relation to the previous all-time high and the fact that it hasnt really pumped this entire run. Im hoping it can shine like SOL in the next couple weeks.'

As for Elrond (EGLD), the crypto trader highlights that the internet-scale blockchain recently printed a golden cross, a bullish signal where the 50-day moving average (MA) crossed above the 200-day MA. Arnold cites another analyst who says that during the two previous golden crosses, EGLD reached a new all-time high in 62 days. Arnold says the analyst predicts EGLD hitting as high as $2,500 on October 18th.

Next up is Ethereum competitor Avalanche (AVAX), which the crypto trader says is gaining momentum as more users flock into the smart contract platform.

We saw what happened with Solana and AVAX, in my opinion, is very similar to a Solana. AVAX is generally gaining in network, popularity, and price action. What theyre doing seems to be attracting a lot of [users].

The last coin on the traders radar is privacy-focused Mina Protocol (MINA), which Arnold says is backed by some of the best venture capital firms in the crypto industry. He adds that long-term holders of MINA have little reason to sell due to the staking mechanics of the coin.

I dont think theres going to be a lot of selling going on anytime soon because the way that the staking works, the highest rewards for the stakers happened in the first eight months or [one] year. So theres really no reason to sell, unless, you can always take profits but I think a lot of people want those staking rewards.

I

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These Five Altcoins Are About To Go Insane, According to Crypto Trader Aaron Arnold - The Daily Hodl

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Analyst Who Called Crypto Crash Updates Bitcoin and Ethereum Outlook, Predicts One Altcoin Likely To Bounce… – The Daily Hodl

A popular pseudonymous crypto analyst who accurately predicted Bitcoin and Ethereums recent pullback is updating his outlook on the markets.

In a new market update, Smart Contracter says Ethereum now appears to have hit a bottom.

I do think weve just hit a major correction low and were probably already bottomed here and I do think well probably get an all-time high.

He highlights Ethereums price action off the bounce in July, noting that the crypto asset appeared to complete a five-wave bullish pattern from the Elliot Waves theory. The Elliot Waves theory is a trading method that aims to predict future price action using crowd psychology that manifests itself on charts through a series of waves.

According to the theory, an asset goes through a significant pull-back (ABC wave) after completing a five-wave cycle in an uptrend.

After topping out just under $4,000 and completing the five-wave impulse, Contracter accurately predicted Ethereums retrace to roughly $2,700. Since the pull-back, ETH has steadily recovered, trading at $3,150 at the time of writing, according to CoinGecko.

The trader is expecting new all-time highs now that it has completed its correction following its five-wave impulse.

I am expecting a new sort of impulsive move similar to this five-wave rise to new all-time highs from here

The analyst says Bitcoin is looking very similar to Ethereum and will most likely move up further after one more ABC wave correction. At the time of writing, Bitcoin is trading at $44,800.

I dare say, similar with Ethereum, were probably gonna go a little bit higher and then well have a nice little ABC [correction]

And then I do think from there, if this is an ABC complete, exactly the same deal again, I dare say were gonna be starting a new impulse to all-time highs.

Smart Contracter also says he is particularly bullish on the smart contract platform Solana (SOL), hypothesizing that it will have one of the strongest rebounds in the altcoin market.

When BTC and ETH bottom I think SOL [will] rebound the hardest [and] hit all-time high the fastest, starting to stack spot at these levels.

Ill average down if need be, no actionable setup just yet more of a knife catch hunch.

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Analyst Who Called Crypto Crash Updates Bitcoin and Ethereum Outlook, Predicts One Altcoin Likely To Bounce... - The Daily Hodl

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