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Microsoft will build new $1B data center in northwest Indiana – Local News Digital

Courtesy-Microsoft Facebook page

LA PORTE, Ind. Governor Eric J. Holcomb announced Tuesday that Microsoft will invest $1 billion to establish a new data center in northwest Indiana. The new La Porte facility will create up to 200 jobs by the end of 2032. It will accelerate cloud computing infrastructure to support technology and artificial intelligence growth.

Indiana is committed to being a central hub in the global economy of the future, and this latest announcement ensures Hoosier communities and talent will be key to widespread advancements in cloud and artificial intelligence technology, said Gov. Holcomb.

Microsoft, headquartered in Redmond, Washington, will construct a new 245,000-square-foot data center on 489 acres at the Radius Industrial Park in La Porte. The campus will help power the Microsoft Cloud and support the next-level digital transformation spurred by the widespread adoption of cloud computing and AI (artificial intelligence). It will join the companys worldwide network of cloud computing infrastructure of more than 60 Azure regions, more than 300 data centers, over 280,000 kilometers of network, and over 190 edge sites.

The technology company will look to fill several positions, including critical environment engineers, IT technicians and managers, inventory and asset technicians and managers, security personnel, and site managers.

The timeline for construction and operations of the new data center is dependent on the design, planning, and permitting process, which will start in cooperation with the City of La Porte later this year.

Tuesdays news marks Indianas fourth strategically located major planned data center announcement in 2024. Together, these Fortune 500 businesses plan to invest $14.8 billion in cloud computing and storage infrastructure in communities and regions across Indiana, creating 1,500 new jobs in Fort Wayne, Jeffersonville, La Porte, and New Carlisle.

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Cloud Security Alliance Survey Finds 70% of Organizations Have Established Dedicated SaaS Security Teams – Dark Reading

PRESS RELEASE

NATIONAL HARBOR, Md.--(BUSINESS WIRE)--Gartner Security and Risk Management Summit-- Seventy percent of organizations have prioritized investment in SaaS security, establishing dedicated SaaS security teams, despite economic uncertainty and workforce reductions. This was a key finding in the fourthAnnual SaaS Security Survey Report: 2025 CISO Plans and Prioritiesreleased today by theCloudSecurity Alliance(CSA), the worlds leading organization dedicated to defining standards, certifications, and best practices to help ensure a secure cloud computing environment.

Commissioned byAdaptive Shield, the leader in SaaS security, the survey found that 39% of organizations are increasing SaaS cybersecurity budgets compared to last year.

Coming off a year in which economic uncertainty and layoffs were making headlines, these results speak volumes to organizations realization that even the most secure systems are vulnerable to increasingly inventive threat actors, said Hillary Baron, lead author and Senior Technical Director for Research, Cloud Security Alliance.

Additional key findings include:

SaaS security dedicated teams are established.For the first time, the survey identified the existence of SaaS-specific security roles: 57% of respondents have a SaaS security team of at least two dedicated full-time employees and another 13% have allocated a dedicated full-time employee.

Organizations managed to improve their key SaaS security capabilities. Full visibility into the SaaS stack has nearly doubled since last year, leaving companies in much better positions when it comes to preventing breaches and detecting threats. Seventy percent of organizations report having moderate to full visibility into their SaaS applications.

SaaS security challenges stem from using the wrong tool. Organizations are still struggling to manage misconfigurations, connected apps, and visibility into security risks. The most difficult areas to manage in SaaS security, according to the respondents, are achieving visibility into business-critical apps (73%); tracking and monitoring security risks from third-party connected apps (65%); locating and fixing SaaS misconfigurations (65%); ensuring data governance and privacy (63%); and aligning SaaS application settings with compliance standards (61%). These challenges stem from using tools such as CASB and Manual Audits. Companies that have adopted SaaS Security Posture Management (SSPM) are more than twice as likely to have full visibility into their SaaS stack 62% of these organizations are able to oversee over 75% of their SaaS environment compared to those that utilize other tools and manual processes in their strategy (31%).

Despite challenges, SaaS security investment is paying off.The challenges presented clearly demonstrate that organizations are taking SaaS security seriously. In fact, the survey identified a positive trend: 25% of respondents experienced a SaaS security incident in the past two years, compared with 53% last year. The most common security incidents reported were data breaches (52%) and data leakage (50%), followed by unauthorized access (44%) and malicious applications (38%).

To be well-equipped to tackle todays most sophisticated threats, large enterprises now understand that investments in preventative methods are the right approach. Organizations have accumulated a wide range of tools that cover single use cases, leaving them exposed from new attack surfaces, and forcing them to manage many different solutions, said Maor Bin, CEO and co-founder, Adaptive Shield.

I am not surprised to see the major leap in SaaS maturity, this is 100% aligned with the exponential and rapidly growing demand we identify in the market. Just like Cloud Security Posture Management (CSPM) covers any security use case in Cloud Infrastructures, SaaS Security Posture Management (SSPM) is all about consolidation of SaaS security attack surfaces.

The survey was conducted online by CSA in January 2024 and received 478 responses from IT and security professionals representing large organizations in various industries and locations. CSAs research analysts performed the data analysis and interpretation for this report. Sponsors are CSA Corporate Members who support the research projects findings but have no added influence on the content development or editing rights of CSA research.

Review the completeAnnual SaaS Security Survey Report: 2025 CISO Plans and Priorities.

About Adaptive Shield

Chosen by hundreds of large enterprises, including numerous Fortune 500 companies,Adaptive Shieldcontinues to be the trusted SaaS Security Posture Management (SSPM) and Identity Threat Detection and Response (ITDR) platform that enables security teams to stay on top of their organizations apps, identities and any unusual user behavior in the SaaS ecosystem. Adaptive Shield leads the SaaS security space and is recognized with awards such as Gartner Cool Vendor, Frost & Sullivans Global Technology Innovation Leadership and the Global Infosec Awards 2024.

About Cloud Security Alliance

The Cloud Security Alliance (CSA) is the worlds leading organization dedicated to defining and raising awareness of best practices to help ensure a secure cloud computing environment. CSA harnesses the subject matter expertise of industry practitioners, associations, governments, and its corporate and individual members to offer cloud security-specific research, education, training, certification, events, and products. CSA's activities, knowledge, and extensive network benefit the entire community impacted by cloud from providers and customers to governments,entrepreneurs, and the assurance industry and provide a forum through which different parties can work together to create and maintain a trusted cloud ecosystem. For further information, visit us atwww.cloudsecurityalliance.org, and follow us on Twitter@cloudsa.

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Cloud Management In The Age Of Rapid Cloud Adoption – International Business Times

Spending on cloud services is expected to top $678.8 billion by 2024, up from $312 billion just three years prior. As businesses scramble to take advantage of the cloud's flexibility, security, and cost savings, a new priority has emerged: cloud management mastery.

Cloud management is the practice of controlling an organization's cloud computing resources and services. However, true mastery goes far beyond spinning up virtual machines. It's about ensuring apps perform on disparate cloud platforms and maintain data portability and business continuity. It's about demonstrating compliance and governing access. Most importantly, it's about maximizing the transformative potential that the cloud unlocks.

Cloud management is often necessary as companies increasingly rely on the cloud, because manually handling all the complexity can become impossible. The different environments, services, pricing models, and more may quickly spiral out of control. Robust cloud management allows organizations to centrally govern their entire cloud footprint for efficiency, security, cost optimization, and more.

However, that's often more easily said than done. The core challenge is that major cloud platforms like AWS, Azure, and Google Cloud aren't all cut from the same cloth. Each has proprietary services, pricing models, and APIs that must be tamed. Solutions that work brilliantly on one may fizzle on another. Teams find themselves having to become fluent multi-cloud systems or risk getting steamrolled.

That's where cloud management platforms (CMPs) come in. Adept at handling all cloud management issues, these platforms are polyglot interpreters of the cloud universe. They promise to provide a centralized hub for deploying resources, monitoring costs, enforcing policies, and managing access across any combination of public and private clouds. CMPs strive to help organize, govern, automate, and measure an enterprise's total cloud estates.

There are open-source options like Kubernetes cluster managers and cloud-native tooling from the Big 3 providers themselves. Cloud security platforms also play a crucial role.

While cloud management platforms help organize and optimize cloud operations, cloud security platforms aim to protect those cloud environments from threats. Vendors like Wiz, Lacework, and Palo Alto Networks provide comprehensive cloud security solutions covering areas like vulnerability management, compliance monitoring, network security, and incident response. As cloud footprints rapidly expand, these specialized security platforms are becoming essential in companies' cloud strategies alongside CMPs.

Choosing the right solution requires breaking through the market noise. The most capable CMPs and security providers facilitate self-service, automate tedious processes, and provide granular cost insights. They serve as command centers for disaster recovery, resource optimization, and centralized identity management.

Savvy organizations realize their cloud journey is a multi-year marathon, not a sprint. Stopping to catch their breath and get their cloud management strategies right is a worthy investment. Those who master this discipline will stay ahead in the never-ending arms race toward operational excellence.

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Microsoft ramps up AI, cloud infrastructure in Sweden with $3.2 billion investment deal – ITPro

Microsoft has announced plans for its largest ever investment in Sweden in a bid to expand cloud and AI infrastructure.

The $3.2 billion investment aims to accelerate Sweden's introduction of AI and create long-term benefits for the Swedish economy, the tech giant confirmed.

The company said it also hopes to increase the country's long-term competitiveness by training up a quarter of a million people in AI skills.

"Our investment in Sweden is proof of our confidence in this nation, its government and its potential as a leading player in the AI era," said Brad Smith, vice chair and president at Microsoft.

"This announcement is about more than just technology. It is a commitment to ensure broad access to the tools and skills needed for Sweden's population and economy to flourish in the AI era."

With the new investment, the company's second in the country in the last three years, Microsoft will expand its cloud and AI infrastructure and add 20,000 advanced GPUs to its existing data center regions in Sandviken, Gvle, and Staffanstorp.

Working with Swedish partners including Boliden, Gunnebo, Kry, Lindex, and Region Vsterbotten, the company also plans to give 250,000 Swedes - around 2.4% of the entire population - necessary AI skills.

Stay up to date with the latest news and analysis from the world of cloud computing with our twice-weekly newsletter

"AI acts as a catalyst for innovation and drives progress and growth in many industries. In order to fully realize Sweden's potential, we must embrace AI to unlock new opportunities, streamline processes and create solutions to complex challenges," said Johannes Schildt, CEO at Kry.

"Together with Microsoft, we are already seeing good results in how AI reduces administrative tasks and enables our healthcare staff to better focus on patient care."

The training will include technical and vocational training for students designed to help develop their AI skills, tailored education for retraining in industry-specific professions, and expert training in AI for developers.

To guide the programs, the company is establishing an AI Insights Council that brings together leaders in academia, business, and the public sector. The program will be run in collaboration with partners and representatives from, among others, the Employment Service, Linkping University, TechSverige, and partners within Microsoft's Responsible AI Innovation Center.

"Microsoft is committed to increasing accessibility and accelerating the introduction of AI throughout the Nordics, including Denmark, Finland, Iceland, Norway and Sweden," Smith commented.

"We will connect our AI investments to programs and partnerships that support individuals, businesses and long-term economic growth across the region."

Big tech investment in the Nordics has surged in recent years amid a flurry of deals across the region.

In late May, Google announced plans to invest $1 billion to expand data center infrastructure in Finland, for example. The move will see the tech giant use data center waste heat to fuel nearby homes and businesses.

Google has deep ties in Finland, having previously pumped 600 million into expanding data center operations in Hamina.

For both Microsoft and Google, proximity to renewable energy sources has been a key factor in their ongoing expansion across the region. Earlier this year, Google broke ground on its first Norwegian data center, which it said will be 99% carbon free.

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Healthcare Cloud Computing Market – Global Industry Analysis and Forecast (2023-2029) – openPR

Healthcare Cloud Computing Market

Healthcare Cloud Computing Market Overview:

Maximize Market Research is a Business Consultancy Firm that has published a detailed analysis of the " Healthcare Cloud Computing Market". The report includes key business insights, demand analysis, pricing analysis, and competitive landscape. The report provides the current state of the Healthcare Cloud Computing market by thorough analysis, and projections are made up to 2029.

Healthcare Cloud Computing Market Scope and Methodology:

The Healthcare Cloud Computing Market Report uses a wid

e research technique and scope to give readers a thorough understanding of the Healthcare Cloud Computing market's environment, trends, and growth-promoting factors. A wide range of topics are covered in this report, such as the size of the market, its main drivers, opportunities, difficulties, and a competitive analysis. A comprehensive research methodology involving primary and secondary research techniques along with strong data analysis is used in the study to provide insights into the present Healthcare Cloud Computing market scenario and future estimates.

It gives stakeholders a comprehensive understanding of the Healthcare Cloud Computing market by examining numerous market categories and geography. The gathered data is subjected to sophisticated statistical techniques and instruments in order to obtain insightful analysis and accurate projections.

For additional insights into this study, please refer to:https://www.maximizemarketresearch.com/market-report/global-healthcare-cloud-computing-market/6377/

Healthcare Cloud Computing Market Regional Insights:

The research report assessed the state of the Healthcare Cloud Computing market, paying particular attention to regional trends, in North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. The regional analysis offers details on the Healthcare Cloud Computing market circumstances in each of the study's numerous participating countries.

Healthcare Cloud Computing Market Segmentation:

by Pricing Model 1. Pay-as-you-go 2. Spot Pricing

by Component 1. Hardware 2. Software 3. Service

by Deployment Model 1. Private Cloud 2. Public Cloud 3. Hybrid Cloud

by Service Model 1. Software-as-a-service (SaaS) 2. Infrastructure-as-a-service (IaaS) 3. Platform-as-a-service (PaaS)

by Application 1. Nonclinical Information Systems 1.1. Revenue Cycle Management (RCM) 1.2. Automatic Patient Billing (APB) 1.3. Cost Accounting 1.4. Payroll Management Systems 1.5. Claims Management 1.6. Others

by End-User 1. Healthcare Providers 2. Healthcare Payers

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Healthcare Cloud Computing Market Key Players:

1. Oracle Corp. 2. Microsoft Corp. 3. EMC Corp. 4. Cisco Systems Inc. 5. VMWare, Inc. 6. Merge Healthcare, Inc. 7. Iron Mountain, Inc. 8. IBM Corporation 9. Global Net Access (GNAX) 10. Dell Inc. 11. Cleardata Networks, Inc. 12. Carestream Health, Inc. 13. Carecloud Corporation 14. Athenahealth, Inc.

Key questions answered in the Healthcare Cloud Computing Market are:

What is Healthcare Cloud Computing ? What was the Healthcare Cloud Computing market size in 2023? What will be the CAGR at which the Healthcare Cloud Computing market will grow? What is the growth rate of the Healthcare Cloud Computing Market? Which are the factors expected to drive the Healthcare Cloud Computing market growth? What are the different segments of the Healthcare Cloud Computing Market? What growth strategies are the players considering to increase their presence in Healthcare Cloud Computing ? What are the upcoming industry applications and trends for the Healthcare Cloud Computing Market? What are the recent industry trends that can be implemented to generate additional revenue streams for the Healthcare Cloud Computing Market? Who are the leading companies and what are their portfolios in Healthcare Cloud Computing Market? What segments are covered in the Healthcare Cloud Computing Market? Who are the key players in the Healthcare Cloud Computing market? Which application holds the highest potential in the Healthcare Cloud Computing market? What are the key challenges and opportunities in the Healthcare Cloud Computing market? Don't miss the summary of the research report for valuable insights: https://www.maximizemarketresearch.com/request-sample/6377

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global Dialysis Market https://www.maximizemarketresearch.com/market-report/global-dialysis-market/80725/

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This release was published on openPR.

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Microsoft Overtakes AWS with Global Data Center Dominance – Korea IT Times

Cloud Computing Giants Expand Data Center Footprints with Updated Strategies

In recent developments, leading cloud computing companies Microsoft and Amazon have made notable progress in expanding their data center infrastructures, seeking to address the ever-increasing demand from their customers. According to Stocklytics, Microsoft has achieved a significant milestone by establishing over 300 data centers globally, thereby surpassing Amazon Web Services (AWS). This achievement highlights Microsofts assertive growth strategy in the cloud computing sector.

Stocklytics financial analyst, Edith Reads, mentioned that Microsoft is enhancing its data center footprint to cater to the burgeoning demand for high-performance computing (HPC), which is critical for AI workloads. This expansion includes modernizing existing facilities and improving infrastructure to efficiently support customer requirements. In addition, Microsoft has collaborated with Vodafone to refine data center strategies, aiming to provide generative AI, digital services, and cloud solutions to over 300 million businesses and consumers across Europe and Africa.

State of the Cloud Infrastructure Market

Although Microsoft has taken the lead in the number of data centers this year, AWS is not far behind with 215 data centers. Google trails with a substantially lower number of 25 data centers. Despite these figures, Microsoft, Google Cloud, and Amazon Web Services still dominate the cloud services market, together capturing 75% of the $76 billion spent on cloud infrastructure services in the first quarter of 2024. Despite AWS maintaining a 31% market share, it experienced a slight dip from 32% in Q1 2023. Meanwhile, Microsoft saw its market share grow from 24% at the end of 2023 to 25%, indicating positive momentum for the company. Google holds an 11% market share in this competitive landscape.

The growth in Microsofts market share signifies its expanding prominence in cloud infrastructure. Its incremental gain from the previous quarter reflects the company's upward trajectory in cloud capabilities development.

Contrastingly, companies like Meta and Apple have significantly fewer data centers, with counts at 24 and 10, respectively. Despite their lower data center numbers and market shares, these firms, along with other smaller entities, contributed to a $13.5 billion increase in overall cloud market expendituresa 21% rise from the previous year. This growth underscores a robust push by technology firms to advance cloud technologies.

Microsofts Future Data Center Expansion Plans

Since July 2023, Microsoft has secured over 500MW of additional data center space. This expansion paves the way for a potential 5GW of IT capacity available for development. Consequently, the company is set to build twice the number of data centers within the next six months of Q1 2024, accounting for 1GW of capacity and targeting a total of 1.5GW for the first half of 2025.

Furthermore, Microsoft plans to invest approximately $2.9 billion in data center infrastructure in Japan and about $3.16 billion in the UK, particularly for a new data center in North Yorkshire.

To enhance service provision, Microsoft aims to increase the geographical distribution of its data centers. This strategy is intended to bring services closer to customers, minimize network latency, and provide geo-redundant backup and failover capabilities.

Updated Insights for 2025 and Beyond

As cloud computing continues to evolve, Microsofts goal is to maintain its leadership by further expanding its data center capabilities and continuing its collaboration with strategic partners. The company's future ventures are likely to involve more innovative approaches to data center efficiency and sustainability. With the ever-growing demand for cloud services fueled by digital transformation and AI advancements, Microsofts ongoing efforts in enhancing its infrastructure footprint will play a vital role in shaping the future of cloud computing.

Source:Stocklytics

Korea IT Times

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Microsoft, Hitachi Sign $18.9B Generative AI Partnership – AI Business

Hitachi will leverage Microsofts AI and cloud services through a multiyear, multibillion-dollar partnership.

Under the three-year deal, Hitachi will integrate Microsoft cloud services, including the Azure OpenAI Service, into its digital solutions business, Lumada.

Lumada will gain access to OpenAI models through the Azure service, which will aid it in building customers' digital solutions.

Lumada will also have access to GitHub Copilot to assist developers with coding tasks and productivity tools through Copilot for Microsoft 365.

The companies estimate the joint generative AI efforts will generate $18.9 billion in revenues for Lumada in 2024 alone.

Hitachis Lumada is already using Microsofts Generative AI for JP1 Cloud Services to accelerate IT response times.

Hitachi and Microsoft have already been working on a variety of co-creation projects including the development of next-generation digital solutions for the manufacturing and logistics fields and the development of a field-extended metaverse that runs on Microsoft Teams, said Keiji Kojima, Hitachis president and CEO. Under this new agreement, we are excited to further accelerate social innovation by expanding our efforts to social infrastructure areas such as energy and mobility, and by applying generative AI, to improve the productivity of frontline workers, which will become even more important in the future.

Related:Microsoft Launches AI Copilot+ PCs: Fastest, Smartest Windows Devices Yet

Hitachi itself will also leverage Microsofts Copilot solutions to improve worker productivity. It plans to train staff to use generative AI solutions, including Microsofts suite of services.

The Japanese company will also use Azure OpenAI Service to use multimodal foundation models like GPT-4o to improve its customer service efforts.

The partnership will also involve joint cloud-focused projects utilizing generative AI for data center security and sustainability.

Hitachis Railway business already runs a generative AI-powered predictive maintenance tool on Microsoft Azure.

We are entering a new era of AI with the promise to deliver transformative business outcomes across every role and industry, said Satya Nadella, Microsofts chair and CEO. Our expanded partnership with Hitachi will bring together the power of the Microsoft Cloud, including Microsoft Copilot, with Hitachis industry expertise to improve the productivity of 270,000 Hitachi employees and help address customers biggest challenges, including sustainability.

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Introducing USC’s Molinaroli College of Engineering and Computing – University of South Carolina

Posted on: June 6, 2024; Updated on: June 6, 2024 By Gregory Hardy, ghardy@sc.edu

The University of South Carolina College of Engineering and Computing has a new name that reflects the vision and generosity of generations of the Molinaroli family.

The official name, the University of South Carolina Molinaroli College of Engineering and Computing, was announced on Thursday (June 6) during a signage unveiling ceremony at the colleges Swearingen Engineering Center on Main Street.

The Molinaroli family boasts strong ties to South Carolina and a deep commitment to the future of the university and the Palmetto State. Seven family members have graduated from USC since the 1930s and another will begin this fall. Their engineering impact spans from the Charleston Navy Yard to the South Carolina Department of Transportation and Johnson Controls.

The $30 million investment initiated by 1983 alumnus Alex Molinaroli and his wife, Kristin Ihle Molinaroli, will be used to establish the college as a leading educational and research institution throughout the Mid-Atlantic and Southeast and a driving force behind South Carolinas economic growth.

Among those expressing gratitude Thursday was USC President Michael Amiridis, who served as the dean of the College of Engineering and Computing from 2006 to 2009.

With this extraordinary gift from Alex and Kristin Molinaroli, we are embarking on a new era for the College of Engineering and Computing, Amiridis said. Their generous commitment will empower the college to enhance its academic stature and explore its fullest potential for exceptional education, research, workforce development and economic impact in South Carolina and beyond.

This marks the universitys fourth academic unit to be named for a donor. The Darla Moore School of Business was named for financial investor and alumna Darla Moore in 1998, and the Arnold School of Public Health was named in 2000 for business leader Norman J. Arnold. Most recently, the Joseph F. Rice School of Law was named in November 2023 for plaintiffs trial lawyer and alumnus Joe Rice.

"A degree from the University of South Carolina can change your life and be an enabler to provide generational change for your family," says Alex Molinaroli. "The University of South Carolina always was and still is a family affair. It is a privilege for my familys name to be associated with the College of Engineering and Computing as it becomes an incubator and foundation developer for the students who will be the next Fortune 100 CEOs and successful entrepreneurs."

The former CEO of Johnson Controls, Alex Molinaroli has been a strong advocate of his alma mater for many years. He has played a pivotal role, offering valuable insights and guidance to college leadership. His previous contributions helped spur innovation and provide opportunities for student advancement.

"The University of South Carolina always was and still is a family affair. It is a privilege for my familys name to be associated with the College of Engineering and Computing as it becomes an incubator and foundation developer for the students who will be the next Fortune 100 CEOs and successful entrepreneurs."

The current gift will support the creation of new, high-demand programs; student and faculty recruitment; facility and equipment enhancements; and research start-ups.

The generous gift honors multiple generations of the Molinaroli family, including Alexs father, Adrian (51), and uncle, Remo (34), who were both first-generation engineering students at USC; his aunt, Elenora (33); his brother, Raymond (91), who is a Lowcountry civil engineer; and two cousins, Charles (65) and Marion (69).

We are grateful for the Molinarolis extraordinary generosity and shared vision for our colleges role in shaping a better future for our state, region and nation, says Hossein Haj-Hariri, dean of the College of Engineering and Computing. Their gift will enable us to enhance our educational, research and partnership efforts to transform our state.

Founded in 1909, the Molinaroli College of Engineering and Computing offers high-quality education through 40 degree programs, including the states only aerospace, biomedical and graduate nuclear engineering programs, as well as numerous computing and AI options.

Nearly 70 percent of students are South Carolinians, and a significant majority of alumni choose to apply their skills within our state's borders.

The colleges thriving academic and research excellence continue to drive economic growth and spur social mobility in the Palmetto State. Leading in energy systems, advanced manufacturing and intelligent infrastructure research, the college will set a university record in fiscal year 2024, receiving over $70 million in sponsored awards.

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Howard University engineering school gets a record $5 million donation – WTOP

Howard University's College of Engineering and Architecture has received a $5 million gift from design software giant Autodesk, the school's largest-single unrestricted donation in its 90-year history.

Howard Universitys College of Engineering and Architecture has received a $5 million gift from design software giant Autodesk, the schools largest-single unrestricted donation in its 90-year history.

Last year, Autodesk donated $1 million to Howard Universitys Department of Mechanical Engineering.

The school will use the latest gift to fund its new state-of-the-art design and make lab, which it plans to unveil this fall. In addition to interdisciplinary collaboration for Howard University students, the labor will be used for K-12 programs for young students

Autodesk offers its design software suites to students and educators for free worldwide. Howard Universitys College of Engineering and Architecture has been using Autodesk software in classrooms for the past six years.

Howard is a leader in graduating Black engineers, and this gift will expand our ability to provide our students with the best and latest resources throughout the course of their education here, said Howard University president Ben Vinson III.

Howard quotes research from career and jobs website Zippia that found only 3% of mechanical engineers in the U.S. are Black. Howard said it is committed to increasing opportunities.

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2024 WTOP. All Rights Reserved. This website is not intended for users located within the European Economic Area.

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High-yield porphyrin production through metabolic engineering and biocatalysis – Nature.com

Hiroto, S., Miyake, Y. & Shinokubo, H. Synthesis and functionalization of porphyrins through organometallic methodologies. Chem. Rev. 117, 29103043 (2017).

Article CAS PubMed Google Scholar

Barr, H. et al. Eradication of high-grade dysplasia in columnar-lined (Barretts) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 348, 584585 (1996).

Article CAS PubMed Google Scholar

Surdel, M. C. et al. Antibacterial photosensitization through activation of coproporphyrinogen oxidase. Proc. Natl Acad. Sci. USA 114, E6652E6659 (2017).

Article CAS PubMed PubMed Central Google Scholar

Drury, S. L. et al. Simultaneous exposure to intracellular and extracellular photosensitizers for the treatment of Staphylococcus aureus infections. Antimicrob. Agents Chemother. 65, e0091921 (2021).

Poulos, T. L. Heme enzyme structure and function. Chem. Rev. 114, 39193962 (2014).

Article CAS PubMed PubMed Central Google Scholar

Zhang, J. et al. Recent advances in microbial production of high-value compounds in the tetrapyrrole biosynthesis pathway. Biotechnol. Adv. 55, 107904 (2022).

Article CAS PubMed Google Scholar

Choi, K. R., Yu, H. E., Lee, H. & Lee, S. Y. Improved production of heme using metabolically engineered Escherichia coli. Biotechnol. Bioeng. 119, 31783193 (2022).

Article CAS PubMed Google Scholar

Zhang, W., Lai, W. & Cao, R. Energy-related small molecule activation reactions: oxygen reduction and hydrogen and oxygen evolution reactions catalyzed by porphyrin- and corrole-based systems. Chem. Rev. 117, 37173797 (2017).

Article CAS PubMed Google Scholar

Singh, S. et al. Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics. Chem. Rev. 115, 1026110306 (2015).

Article CAS PubMed PubMed Central Google Scholar

Espinas, N. A., Kobayashi, K., Takahashi, S., Mochizuki, N. & Masuda, T. Evaluation of unbound free heme in plant cells by differential acetone extraction. Plant Cell Physiol. 53, 13441354 (2012).

Article CAS PubMed Google Scholar

In, M.-J., Kim, D. C., Chae, H. J. & Oh, N.-S. Effects of degree of hydrolysis and pH on the solubility of heme-iron enriched peptide in hemoglobin hydrolysate. Biosci. Biotechnol. Biochem. 67, 365367 (2003).

Article CAS PubMed Google Scholar

Lichtenthaler, H. K. & Buschmann, C. Extraction of phtosynthetic tissues: chlorophylls and carotenoids. Curr. Protoc. Food Anal. Chem. 1, F4.2.1F4.2.6 (2001).

Article Google Scholar

Kwon Seok, J., de Boer Arjo, L., Petri, R. & Schmidt-Dannert, C. High-level production of porphyrins in metabolically engineered Escherichia coli: systematic extension of a pathway assembled from overexpressed genes involved in heme biosynthesis. Appl. Environ. Microbiol. 69, 48754883 (2003).

Article PubMed PubMed Central Google Scholar

Bali, S. et al. Molecular hijacking of siroheme for the synthesis of heme and d1 heme. Proc. Natl Acad. Sci. USA 108, 1826018265 (2011).

Article CAS PubMed PubMed Central Google Scholar

Dailey Harry, A. et al. Prokaryotic heme biosynthesis: multiple pathways to a common essential product. Microbiol. Mol. Biol. Rev. 81, e00048-16 (2017).

PubMed PubMed Central Google Scholar

Dailey, H. A., Gerdes, S., Dailey, T. A., Burch, J. S. & Phillips, J. D. Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin. Proc. Natl Acad. Sci. USA 112, 22102215 (2015).

Article CAS PubMed PubMed Central Google Scholar

Fang, H. et al. Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B12. Nat. Commun. 9, 4917 (2018).

Article PubMed PubMed Central Google Scholar

Chen, G. E. et al. Complete enzyme set for chlorophyll biosynthesis in Escherichia coli. Sci. Adv. 4, eaaq1407 (2018).

Article PubMed PubMed Central Google Scholar

Nielsen, M. T. et al. Assembly of highly standardized gene fragments for high-level production of porphyrins in E. coli. ACS Synth. Biol. 4, 274282 (2015).

Article CAS PubMed Google Scholar

Zhang, J. et al. Heme biosensor-guided in vivo pathway optimization and directed evolution for efficient biosynthesis of heme. Biotechnol. Biofuels Bioprod. 16, 33 (2023).

Article PubMed PubMed Central Google Scholar

Dai, J. et al. Differential gene content and gene expression for bacterial evolution and speciation of Shewanella in terms of biosynthesis of heme and heme-requiring proteins. BMC Microbiol. 19, 173 (2019).

Article PubMed PubMed Central Google Scholar

Ouchane, S., Picaud, M., Therizols, P., Reiss-Husson, F. & Astier, C. Global regulation of photosynthesis and respiration by FnrL: the first two targets in the tetrapyrrole pathway. J. Biol. Chem. 282, 76907699 (2007).

Article CAS PubMed Google Scholar

Toriya, M. et al. Zincphyrin, a novel coproporphyrin III with zinc from Streptomyces sp. J. Antibiot. (Tokyo) 46, 196200 (1993).

Article CAS PubMed Google Scholar

Nguyen, H. T. et al. Exploration of cryptic organic photosensitive compound as Zincphyrin IV in Streptomyces venezuelae ATCC 15439. Appl. Microbiol. Biotechnol. 104, 713724 (2020).

Article CAS PubMed Google Scholar

Cleary, J. L., Kolachina, S., Wolfe, B. E. & Sanchez, L. M. Coproporphyrin III produced by the bacterium Glutamicibacter arilaitensis binds zinc and is upregulated by fungi in cheese rinds. mSystems. 3, e00036-18 (2018).

Zhao, X. R., Choi, K. R. & Lee, S. Y. Metabolic engineering of Escherichia coli for secretory production of free haem. Nat. Catal. 1, 720728 (2018).

Article CAS Google Scholar

Ko, Y. J. et al. Animal-free heme production for artificial meat in Corynebacterium glutamicum via systems metabolic and membrane engineering. Metab. Eng. 66, 217228 (2021).

Article CAS PubMed Google Scholar

Ishchuk, O. P. et al. Genome-scale modeling drives 70-fold improvement of intracellular heme production in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 119, e2108245119 (2022).

Article CAS PubMed PubMed Central Google Scholar

Choi, K. R., Yu, H. E. & Lee, S. Y. Production of zinc protoporphyrin IX by metabolically engineered Escherichia coli. Biotechnol. Bioeng. 119, 33193325 (2022).

Article CAS PubMed Google Scholar

Nelson, N. Metal ion transporters and homeostasis. EMBO J. 18, 43614371 (1999).

Article CAS PubMed PubMed Central Google Scholar

Frunzke, J., Gtgens, C., Brocker, M. & Bott, M. Control of heme homeostasis in Corynebacterium glutamicum by the two-component system HrrSA. J. Bacteriol. 193, 12121221 (2011).

Article CAS PubMed PubMed Central Google Scholar

Koripella, R. K. et al. Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus. J. Biol. Chem. 287, 3025730267 (2012).

Article CAS PubMed PubMed Central Google Scholar

Kojima, I., Maruhashi, K., Sato, H. & Fujiwara, Y. A highly active producer of coproporphyrin III and uroporphyrin III. J. Ferment. Bioeng. 76, 527529 (1993).

Article CAS Google Scholar

Zhang, L. et al. Phosphate limitation increases coenzyme Q10 production in industrial Rhodobacter sphaeroides HY01. Synth. Syst. Biotechnol. 4, 212219 (2019).

Article PubMed PubMed Central Google Scholar

Shi, T. et al. Screening and engineering of high-activity promoter elements through transcriptomics and red fluorescent protein visualization in Rhodobacter sphaeroides. Synth. Syst. Biotechnol. 6, 335342 (2021).

Article CAS PubMed PubMed Central Google Scholar

Lee, S. Q. E., Tan, T. S., Kawamukai, M. & Chen, E. S. Cellular factories for coenzyme Q10 production. Microb. Cell. Fact. 16, 39 (2017).

Article PubMed PubMed Central Google Scholar

Lu, W. et al. Identification and elimination of metabolic bottlenecks in the quinone modification pathway for enhanced coenzyme Q10 production in Rhodobacter sphaeroides. Metab. Eng. 29, 208216 (2015).

Article CAS PubMed Google Scholar

Wang, Z.-J. et al. Oxygen uptake rate controlling strategy balanced with oxygen supply for improving coenzyme Q10 production by Rhodobacter sphaeroides. Biotechnol. Bioprocess Eng. 25, 459469 (2020).

Article CAS Google Scholar

Klaus, O. et al. Engineering phototrophic bacteria for the production of terpenoids. Curr. Opin. Biotechnol. 77, 102764 (2022).

Article CAS PubMed Google Scholar

Qiang, S. et al. Elevated -carotene synthesis by the engineered rhodobacter sphaeroides with enhanced CrtY expression. J. Agric. Food Chem. 67, 95609568 (2019).

Article CAS PubMed Google Scholar

Orsi, E. et al. Growth-uncoupled isoprenoid synthesis in Rhodobacter sphaeroides. Biotechnol. Biofuels 13, 123 (2020).

Article CAS PubMed PubMed Central Google Scholar

Hu, J., Yang, H., Wang, X., Cao, W. & Guo, L. Strong pH dependence of hydrogen production from glucose by Rhodobacter sphaeroides.Int. J. Hydrog. Energy 45, 94519458 (2020).

Article CAS Google Scholar

Li, S. et al. Photoautotrophic hydrogen production of Rhodobacter sphaeroides in a microbial electrosynthesis cell. Bioresour. Technol. 320, 124333 (2021).

Article CAS PubMed Google Scholar

Orsi, E., Beekwilder, J., Eggink, G., Kengen, S. W. M. & Weusthuis, R. A. The transition of Rhodobacter sphaeroides into a microbial cell factory. Biotechnol. Bioeng. 118, 531541 (2021).

Article CAS PubMed Google Scholar

Oh, J.-I. & Kaplan, S. Generalized approach to the regulation and integration of gene expression. Mol. Microbiol. 39, 11161123 (2001).

Article CAS PubMed Google Scholar

Imam, S., Noguera, D. R. & Donohue, T. J. Global analysis of photosynthesis transcriptional regulatory networks. PLoS Genet. 10, e1004837 (2014).

Article PubMed PubMed Central Google Scholar

Kang, Z. et al. Recent advances in microbial production of -aminolevulinic acid and vitamin B12. Biotechnol. Adv. 30, 15331542 (2012).

Article CAS PubMed Google Scholar

Nishikawa, S. et al. Rhodobacter sphaeroides mutants which accumulate 5-aminolevulinic acid under aerobic and dark conditions. J. Biosci. Bioeng. 87, 798804 (1999).

Article CAS PubMed Google Scholar

Urakami, T. & Yoshida, T. Production of ubiquinone and bacteriochlorophyll a by Rhodobacter sphaeroides and Rhodobacter sulfidophilus. J. Ferment. Bioeng. 76, 191194 (1993).

Article CAS Google Scholar

Zeilstra-Ryalls, J. H. & Kaplan, S. Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the role of the fnrL gene. J. Bacteriol. 177, 64226431 (1995).

Article CAS PubMed PubMed Central Google Scholar

Wei, W. et al. Lysine acetylation regulates the function of the global anaerobic transcription factor FnrL in Rhodobacter sphaeroides. Mol. Microbiol. 104, 278293 (2017).

Article CAS PubMed Google Scholar

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