Cloud Hosting

Tinelli, F. et al. Vascular remodeling in moyamoya angiopathy: From peripheral blood mononuclear cells to endothelial cells. Int. J. Mol. Sci. 21(16), 5763 (2020).

Article CAS PubMed PubMed Central Google Scholar

Kuroda, S. & Houkin, K. Moyamoya disease: Current concepts and future perspectives. Lancet Neurol. 7(11), 10561066 (2008).

Article PubMed Google Scholar

Goto, Y. & Yonekawa, Y. Worldwide distribution of moyamoya disease. Neurol. Med. Chir. 32(12), 883886 (1992).

Article CAS Google Scholar

Kuriyama, S. et al. Prevalence and clinicoepidemiological features of moyamoya disease in Japan: Findings from a nationwide epidemiological survey. Stroke 39(1), 4247 (2008).

Article PubMed Google Scholar

Kamada, F. et al. A genome-wide association study identifies RNF213 as the first Moyamoya disease gene. J. Hum. Genet. 56(1), 3440 (2011).

Article CAS PubMed Google Scholar

Bang, O. Y., Fujimura, M. & Kim, S. K. the pathophysiology of moyamoya disease: An update. J. Stroke 18(1), 1220 (2016).

Article PubMed PubMed Central Google Scholar

Kim, E. H. et al. Importance of RNF213 polymorphism on clinical features and long-term outcome in moyamoya disease. J. Neurosurg. 124(5), 12211227 (2016).

Article CAS PubMed Google Scholar

Kang, H. S. et al. Plasma matrix metalloproteinases, cytokines and angiogenic factors in moyamoya disease. J. Neurol. Neurosurg. Psychiatry 81(6), 673678 (2010).

Article PubMed Google Scholar

Jaipersad, A. S. et al. The role of monocytes in angiogenesis and atherosclerosis. J. Am. Coll. Cardiol. 63(1), 111 (2014).

Article CAS PubMed Google Scholar

Morishita, R. et al. Impairment of collateral formation in lipoprotein(a) transgenic mice: Therapeutic angiogenesis induced by human hepatocyte growth factor gene. Circulation 105(12), 14911496 (2002).

Article CAS PubMed Google Scholar

Schning, M. et al. Antiphospholipid antibodies in cerebrovascular ischemia and stroke in childhood. Neuropediatrics 25(1), 814 (1994).

Article PubMed Google Scholar

Suzuki, S. et al. Moyamoya disease complicated by Graves disease and type 2 diabetes mellitus: Report of two cases. Clin. Neurol. Neurosurg. 113(4), 325329 (2011).

Article PubMed Google Scholar

Wanifuchi, H. et al. Autoimmune antibody in moyamoya disease. No Shinkei Geka 14(1), 3135 (1986).

CAS PubMed Google Scholar

Lin, R. et al. Clinical and immunopathological features of Moyamoya disease. PLoS ONE 7(4), e36386 (2012).

Article ADS CAS PubMed PubMed Central Google Scholar

Fujimura, M. et al. Increased serum production of soluble CD163 and CXCL5 in patients with moyamoya disease: Involvement of intrinsic immune reaction in its pathogenesis. Brain Res. 1679, 3944 (2018).

Article CAS PubMed Google Scholar

Kanehisa, M. Toward understanding the origin and evolution of cellular organisms. Protein Sci. 28(11), 19471951 (2019).

Article CAS PubMed PubMed Central Google Scholar

Kanehisa, M. & Goto, S. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28(1), 2730 (2000).

Article CAS PubMed PubMed Central Google Scholar

Kanehisa, M. et al. KEGG for taxonomy-based analysis of pathways and genomes. Nucleic Acids Res. 51(D1), D587-d592 (2023).

Article CAS PubMed Google Scholar

Langfelder, P. & Horvath, S. WGCNA: An R package for weighted correlation network analysis. BMC Bioinform. 9, 559 (2008).

Article Google Scholar

Degenhardt, F., Seifert, S. & Szymczak, S. Evaluation of variable selection methods for random forests and omics data sets. Brief Bioinform. 20(2), 492503 (2019).

Article PubMed Google Scholar

Friedman, J., Hastie, T. & Tibshirani, R. Regularization paths for generalized linear models via coordinate descent. J. Stat. Softw. 33(1), 122 (2010).

Article PubMed PubMed Central Google Scholar

Newman, A. M. et al. Robust enumeration of cell subsets from tissue expression profiles. Nat. Methods 12(5), 453 (2015).

Article CAS PubMed PubMed Central Google Scholar

Huang, J. et al. Weighted gene co-expression network analysis and CIBERSORT screening of key genes related to m6A methylation in Hirschsprungs disease. Front. Genet. 14, 1183467 (2023).

Article CAS PubMed PubMed Central Google Scholar

Asselman, C. et al. Moyamoya disease emerging as an immune-related angiopathy. Trends Mol. Med. 28(11), 939950 (2022).

Article PubMed Google Scholar

Sigdel, T. K. et al. Immune response profiling identifies autoantibodies specific to Moyamoya patients. Orphanet. J. Rare Dis. 8, 45 (2013).

Article PubMed PubMed Central Google Scholar

Jin, F. & Duan, C. Identification of immune-infiltrated hub genes as potential biomarkers of Moyamoya disease by bioinformatics analysis. Orphanet. J. Rare Dis. 17(1), 80 (2022).

Article PubMed PubMed Central Google Scholar

Roder, C. et al. Common genetic polymorphisms in moyamoya and atherosclerotic disease in Europeans. Childs Nerv. Syst. 27(2), 245252 (2011).

Article PubMed Google Scholar

Achrol, A. S. et al. Pathophysiology and genetic factors in moyamoya disease. Neurosurg. Focus 26(4), E4 (2009).

Article PubMed Google Scholar

Guo, D. C. et al. Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am. J. Hum. Genet. 84(5), 617627 (2009).

Article CAS PubMed PubMed Central Google Scholar

Ikeda, E. Systemic vascular changes in spontaneous occlusion of the circle of Willis. Stroke 22(11), 13581362 (1991).

Article CAS PubMed Google Scholar

Sato-Maeda, M. et al. Transient middle cerebral artery occlusion in mice induces neuronal expression of RNF213, a susceptibility gene for moyamoya disease. Brain Res. 1630, 5055 (2016).

Article CAS PubMed Google Scholar

Quintos, J. B., Guo, M. H. & Dauber, A. Idiopathic short stature due to novel heterozygous mutation of the aggrecan gene. J. Pediatr. Endocrinol. Metab. 28(78), 927932 (2015).

CAS PubMed PubMed Central Google Scholar

Gkourogianni, A. et al. Clinical characterization of patients with autosomal dominant short stature due to aggrecan mutations. J. Clin. Endocrinol. Metab. 102(2), 460469 (2017).

Article PubMed Google Scholar

Lin, L. et al. A high proportion of novel ACAN mutations and their prevalence in a large cohort of chinese short stature children. J. Clin. Endocrinol. Metab. 106(7), e2711e2719 (2021).

Article PubMed PubMed Central Google Scholar

Vafaeie, F. et al. ACAN, MDFI, and CHST1 as candidate genes in gastric cancer: A comprehensive insilco analysis. Asian Pac. J. Cancer Prev. 23(2), 683694 (2022).

Article CAS PubMed PubMed Central Google Scholar

Koh, Y. W. et al. Association between the CpG island methylator phenotype and its prognostic significance in primary pulmonary adenocarcinoma. Tumour Biol. 37(8), 1067510684 (2016).

Article CAS PubMed Google Scholar

Kim, S. M. et al. Endothelial dysfunction induces atherosclerosis: Increased aggrecan expression promotes apoptosis in vascular smooth muscle cells. BMB Rep. 52(2), 145150 (2019).

Article CAS PubMed PubMed Central Google Scholar

Jung, K. H. et al. Circulating endothelial progenitor cells as a pathogenetic marker of moyamoya disease. J. Cereb. Blood Flow Metab. 28(11), 17951803 (2008).

Article CAS PubMed Google Scholar

Kim, J. H. et al. Decreased level and defective function of circulating endothelial progenitor cells in children with moyamoya disease. J. Neurosci. Res. 88(3), 510518 (2010).

Article CAS PubMed Google Scholar

Kashem, M. A. et al. The potential role of FREM1 and its isoform TILRR in HIV-1 acquisition through mediating inflammation. Int. J. Mol. Sci. 22(15), 7825 (2021).

Article CAS PubMed PubMed Central Google Scholar

Li, H. N. et al. Elevated expression of FREM1 in breast cancer indicates favorable prognosis and high-level immune infiltration status. Cancer Med. 9(24), 95549570 (2020).

Article CAS PubMed PubMed Central Google Scholar

Karim, R. et al. Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocytes innate immune response. PLoS Pathog. 9(5), e1003384 (2013).

Article CAS PubMed PubMed Central Google Scholar

Gu, Y. et al. The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells. Cell Death Dis. 9(5), 459 (2018).

Article PubMed PubMed Central Google Scholar

Jain, M. et al. TOP2A is overexpressed and is a therapeutic target for adrenocortical carcinoma. Endocr. Relat. Cancer 20(3), 361370 (2013).

Article CAS PubMed PubMed Central Google Scholar

Olsen, K. E. et al. Amplification of HER2 and TOP2A and deletion of TOP2A genes in breast cancer investigated by new FISH probes. Acta Oncol. 43(1), 3542 (2004).

Article CAS PubMed Google Scholar

Moretti, E. et al. TOP2A protein by quantitative immunofluorescence as a predictor of response to epirubicin in the neoadjuvant treatment of breast cancer. Future Oncol. 9(10), 14771487 (2013).

Article CAS PubMed Google Scholar

Masuda, J., Ogata, J. & Yutani, C. Smooth muscle cell proliferation and localization of macrophages and T cells in the occlusive intracranial major arteries in moyamoya disease. Stroke 24(12), 19601967 (1993).

Article CAS PubMed Google Scholar

Weng, L. et al. Association of increased Treg and Th17 with pathogenesis of moyamoya disease. Sci. Rep. 7(1), 3071 (2017).

Article ADS PubMed PubMed Central Google Scholar

Yamamoto, M. et al. Increase in elastin gene expression and protein synthesis in arterial smooth muscle cells derived from patients with Moyamoya disease. Stroke 28(9), 17331738 (1997).

Article CAS PubMed Google Scholar

Roder, C. et al. Polymorphisms in TGFB1 and PDGFRB are associated with Moyamoya disease in European patients. Acta Neurochir. (Wien) 152(12), 21532160 (2010).

Article PubMed Google Scholar

Here is the original post:
Identification of diagnostic markers for moyamoya disease by combining bulk RNA-sequencing analysis and machine ... - Nature.com