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We have 11 divisions and offices whose work spans the spectrum of translational science. Together, they identify and devise plans for new opportunities, build tools and technologies, support research here and beyond, train scientists, and so much more.

The Office of the Director develops and provides leadership for the centers translational science programs, manages and directs executive-level activities, and provides policy guidance and coordination for each of the centers components.

The Division of Clinical Innovation (DCI) plans, conducts and supports research across the clinical phases of the translational science spectrum. DCI plans, conducts and supports research to develop new methods and technologies to enhance clinical processes, as well as to evaluate existing and developing approaches, technologies, and processes in the clinical spectrum. It also supports training programs relevant to clinical phases of translational science and allocates resources to clinical and translational infrastructure and investigators.

The Division of Extramural Activities advises NCATS leadership on issues related to policy and procedures for extramural activities. It works closely with other parts of NIH to develop, coordinate and implement new extramural policies for research grants and contracts. Its Office of the Director manages the membership and operations of the NCATS Advisory Council and Cures Acceleration Network Review Board, and it oversees and coordinates prize competitions and all aspects of initiative management. It also coordinates the receipt and referral of grant/advisory/council applications, among other activities.

The Division of Preclinical Innovation (DPI) plans and conducts collaborative research projects across the preclinical phases of the translational science spectrum, using both internal and contract resources to advance them. DPI plans, conducts and collaborates on research to develop new methods and technologies to enhance preclinical processes, as well as to evaluate existing and developing approaches, technologies, and processes in the preclinical spectrum. It also supports training programs relevant to preclinical phases of translational science and allocates DPI resources to preclinical extramural and intramural investigators.

The Division of Rare Diseases Research Innovation facilitates and coordinates many of our rare disease programs as well as NIH-wide activities involving research for a broad array of rare diseases. DRDRI also develops and manages rare disease information resources for patients and patient advocacy organizations.

The Office of Administrative Management directs the administrative, information technology and financial operations management of the center. It also oversees personnel management and workforce planning.

The Office of Drug Development Partnership Programs (ODDPP) promotes innovations that improve the efficiency of drug development from target identification including expanding the target landscape through early-stage clinical trials. Programs administered by ODDPP often involve partnerships with the private sector, other parts of NIH or the U.S. Government, and NCATS own intramural scientists. The ODDPP also works with national and international stakeholders, providing leadership for the national response to public health emergencies.

The Office of Policy, Communications and Education develops and communicates critical priorities for NCATS in a highly collaborative manner.

The Office of Special Initiatives (OSI) addresses translational problems with innovative solutions through the development and implementation of disruptive technologies using interdisciplinary approaches and novel public-private partnerships. The programs and initiatives within OSI are intended to be catalytic and transformative, resulting in a paradigm shift in the field. The OSI also takes the lead on NIH-wide research activities that are supported through the NIH Common Fund.

The Office of Strategic Alliances establishes and advances public-private partnerships, as well as develops innovative approaches, policies and methods to reduce, remove or bypass bottlenecks in translational science collaborations.

The Office of Translational Medicine (OTM) uses expertise across clinical and other relevant disciplines to amplify NCATS ability to foster innovative translational science and improve health. The OTM interprets and implements research-related policies, convenes stakeholders, and, in certain circumstances, arbitrates or makes decisions. Topics of interest include human subjects; diversity, equity, inclusion and accessibility; regulation and drug development; clinical research, including clinical trials and clinical epidemiology; and ethics, for which OTM operates a grant program.

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Divisions and Offices - NCBI