Development of a prediction model for the depression level of the … – Nature.com

The results of the demographic characteristics of the study and the average difference in depression levels are shown in Table 2. Females accounted for a higher number than males; females (n=2008, 67.5%) and males (n=967, 32.5%). For the age distribution, ages of 80 or older was the largest with 1475 people (49.6%), followed by ages of 7579 with 755 people (25.4%) and ages of 7074 with 459 people (15.4%). Regarding the level of education, 2107 people (70.8%) had elementary school graduation, and 471 people (15.8%) had middle school graduation. indicating that the majority had a low level of education. When asked about the number of household members, two people accounted for the largest portion with 1459 people (49.0%), showing that the majority lived with one more person. As for having disabilities, 2425 people (81.5%) mentioned no, and 550 people (18.5%) stated yes. In terms of participation in economic activities, not participating accounted for more than half of the participants (n=2042, 68.6%).

In terms of depression, 2553 people (85.8%) reported no and 422 people (14.2%) reported yes. Lastly, the average difference between the sociodemographic characteristics and the depression level of the participants was evaluated. As a result, there were significant gender differences (t=3.547, p<0.001) and participation in economic activities (F=7.326, p<0.001), but no differences were found in other factors.

The descriptive statistical results of the main factors are shown in Table 3. Considering that the range of scores for health promoting behavior is from a minimum of 0 to a maximum of 3, an average of 2.2 points can be regarded as a high value. On the other hand, having a standard deviation of 0.72, it can be understood that there was no significant difference in health promotion behavior by the elderly in low-income households. With reference to subjective health awareness, it was found that numerous elderly people had a higher awareness than the average, with an average of 2.8 points. Regarding the level of medical expenses, it was found that the average monthly expenditure was 158,000 won, and the standard deviation was 20.17, indicating a high difference in expenditure among the elderly in low-income households. Family support, social support, and leisure life satisfaction showed average scores of 2.7, 2.6, and 2.3, respectively, which were verified to be in good standing, considering that the range of scores was at least 0 to up to 4.

The relative importance of the predictive factors that contributed to predicting depression in low-income seniors utilizing the feature selection, is shown in Table 4. The higher the order of importance of a predictor, the greater the influence of that factor in predicting the level of depression; the highest ranking was identified as 'leisure life satisfaction.' This result can be interpreted as having the greatest effect on satisfaction in leisure life than other factors when predicting the level of depression of the elderly in low-income households. Furthermore, the factors of subjective health awareness, family support, and social support were found to be in the upper ranks. However, it was noted that the factors of presence or absence of chronic diseases, educational level, disability, and health behavior were distributed in the low ranking. A SHAP summary plot was created (Fig.2), a visualization of how much each explanatory variable affects the prediction of depression. A yellow bar indicates a positive influence on the occurrence of depression. The red and orange bars indicate a negative impact on the occurrence of depression. The red bars were found to be the most influential variables. Regarding leisure life satisfaction, it can be used as an explanatory or a dependent variable. This study used it as an explanatory variable because the subjects were low-income elderly. The relationship between leisure life satisfaction and depression in low-income elderly is often reported as causal, with leisure life satisfaction affecting depression29.

The summary plot of the SHAP values.

In this study, the classification techniques used to develop the most accurate predictive model, predicting the level of depression of the elderly in low-income households, were artificial neural networks, decision trees, logistic regression and random forest analysis. Table 5 is the result of the classification analysis by sequentially applying the wrapper's stepwise method to the relative importance of the factors identified in Table 4. Based on the analysis, it was identified that the decision tree algorithm showed higher predictive power than the other three algorithms. In the case of logistic regression analysis, the prediction accuracy was 73.2%, and the artificial neural network showed 81.8%. On the other hand, the decision tree shows a tendency to increase predictive accuracy as the number of factors increases, except when there is only one input factor. When all 13 factors were input, an accuracy of 97.3%, a sensitivity of 100%, and a specificity of 94.6% were presented. Finally, when forming the decision-making tree, the factor that had the greatest impact was the subjective health awareness factor, followed by leisure life satisfaction, family support, and social support. To ensure that the main outcome was reliable and robust, a sensitivity analysis was conductedby dividing the dependent variable, depression incidence, into two thresholds (15 points or less, 16 points or more); the analysis revealed that the main outcome did not change in Tables 6, 7.

Logistic regression analysis was performed to seek the influence of the predictors of high risk of depression in the elderly from low-income households, and the results are shown in Table 8. The factors that affected the level of depression were gender, number of household members, subjective health awareness, family support, social support, and satisfaction with leisure life. In the case of gender, the probability of developing depression in women was confirmed to be 1.86 times (OR=1.861, 95% CI=1.1732.954) higher than in men. As the number of household members increased by each level, the probability of depression decreased by 0.69 times (OR=0.692, 95% CI=0.5130.933). In subjective health awareness, an increase of each level was associated with a 0.40-fold (OR=0.403, 95% CI=0.3120.522) lower probability of depression. Further, family support (OR=0.613, 95% CI=0.4940.759), social support (OR=0.711, 95% CI=0.5520.916), and leisure life satisfaction (OR=0.425, 95% CI=0.3280.425) showed that the probability of depression decreased by 0.61 times, 0.71 times, and 0.42 times, respectively, as the level increased by each level.

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