Category Archives: Deep Mind
With ChatGPT hype swirling, UK government urges regulators to come up with rules for A.I. – CNBC
The ChatGPT and OpenAI emblem and website.
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The U.K. government on Wednesday published recommendations for the artificial intelligence industry, outlining an all-encompassing approach for regulating the technology at a time when it has reached frenzied levels of hype.
In a white paper to be put forward to Parliament, the Department for Science, Innovation and Technology (DSIT) will outline five principles it wants companies to follow. They are: safety, security and robustness; transparency and explainability; fairness; accountability and governance; and contestability and redress.
Rather than establishing new regulations, the government is calling on regulators to apply existing regulations and inform companies about their obligations under the white paper.
It has tasked the Health and Safety Executive, the Equality and Human Rights Commission, and the Competition and Markets Authority with coming up with "tailored, context-specific approaches that suit the way AI is actually being used in their sectors."
"Over the next twelve months, regulators will issue practical guidance to organisations, as well as other tools and resources like risk assessment templates, to set out how to implement these principles in their sectors," the government said.
"When parliamentary time allows, legislation could be introduced to ensure regulators consider the principles consistently."
Maya Pindeus, CEO and co-founder of AI startup Humanising Autonomy, said the government's move marked a "first step" toward regulating AI.
"There does need to be a bit of a stronger narrative," she said. "I hope to see that. This is kind of planting the seeds for this."
However, she added, "Regulating technology as technology is incredibly difficult. You want it to advance; you don't want to hinder any advancements when it impacts us in certain ways."
The arrival of the recommendations is timely. ChatGPT, the popular AI chatbot developed by the Microsoft-backed company OpenAI, has driven a wave of demand for the technology, and people are using the tool for everything from penning school essays to drafting legal opinions.
ChatGPT has already become one of the fastest-growing consumer applications of all time, attracting 100 million monthly active users as of February. But experts have raised concerns about the negative implications of the technology, including the potential for plagiarism and discrimination against women and ethnic minorities.
AI ethicists are worried about biases in the data that trains AI models. Algorithms have been shown to have a tendency of being skewed in favor men especially white men putting women and minorities at a disadvantage.
Fears have also been raised about the possibility of jobs being lost to automation. On Tuesday, Goldman Sachs warned that as many as 300 million jobs could be at risk of being wiped out by generative AI products.
The government wants companies that incorporate AI into their businesses to ensure they provide an ample level of transparency about how their algorithms are developed and used. Organizations "should be able to communicate when and how it is used and explain a system's decision-making process in an appropriate level of detail that matches the risks posed by the use of AI," the DSIT said.
Companies should also offer users a way to contest rulings taken by AI-based tools, the DSIT said. User-generated platforms like Facebook, TikTok and YouTube often use automated systems to remove content flagged up as being against their guidelines.
AI, which is believed to contribute 3.7 billion ($4.6 billion) to the U.K. economy each year, should also "be used in a way which complies with the UK's existing laws, for example the Equality Act 2010 or UK GDPR, and must not discriminate against individuals or create unfair commercial outcomes," the DSIT added.
On Monday, Secretary of State Michelle Donelan visited the offices of AI startup DeepMind in London, a government spokesperson said.
"Artificial intelligence is no longer the stuff of science fiction, and the pace of AI development is staggering, so we need to have rules to make sure it is developed safely," Donelan said in a statement Wednesday.
"Our new approach is based on strong principles so that people can trust businesses to unleash this technology of tomorrow."
Lila Ibrahim, chief operating officer of DeepMind and a member of the U.K.'s AI Council, said AI is a "transformational technology," but that it "can only reach its full potential if it is trusted, which requires public and private partnership in the spirit of pioneering responsibly."
"The UK's proposed context-driven approach will help regulation keep pace with the development of AI, support innovation and mitigate future risks," Ibrahim said.
It comes after other countries have come up with their own respective regimes for regulating AI. In China, the government has required tech companies to hand over details on their prized recommendation algorithms, while the European Union has proposed regulations of its own for the industry.
Not everyone is convinced by the U.K. government's approach to regulating AI. John Buyers, head of AI at the law firm Osborne Clarke, said the move to delegate responsibility for supervising the technology among regulators risks creating a "complicated regulatory patchwork full of holes."
"The risk with the current approach is that an problematic AI system will need to present itself in the right format to trigger a regulator's jurisdiction, and moreover the regulator in question will need to have the right enforcement powers in place to take decisive and effective action to remedy the harm caused and generate a sufficient deterrent effect to incentivise compliance in the industry," Buyers told CNBC via email.
By contrast, the EU has proposed a "top down regulatory framework" when it comes to AI, he added.
WATCH: Three decades after inventing the web, Tim Berners-Lee has some ideas on how to fix it
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With ChatGPT hype swirling, UK government urges regulators to come up with rules for A.I. - CNBC
What the AI-generated image of Pope Francis means for the imagination – Vox.com
A recent viral image of Pope Francis wearing an unusually hip white puffer jacket was both a fake created by generative AI and an omen that marked the accelerating collapse of a clearly distinguishable boundary between imagination and reality.
Photorealistic images of fictions like Donald Trump getting arrested while stumbling in a sea of cops can now be generated on demand by AI programs like Midjourney, DALL-E 2, and Stable Diffusion. This sets off alarm bells around how misinformation may thrive. But along with risks, AI-generated imagery also offers a great leap forward for the human imagination.
Seeing is believing goes both ways. Image-generating AI will allow us to see realistic depictions of what does not yet exist, expanding the kinds of futures we can imagine as visual realities. The human imagination doesnt build ideas from scratch. Its combinatorial: The mind cobbles together new ideas from accumulated bits and pieces it has been exposed to. AI-generated images will greatly increase the raw material of plausible worlds the mind can imagine inhabiting and, through them, the kinds of futures we perceive as possible.
For example, its one thing to read a description or see an illustration of a futuristic city with inspiring architecture, public transportation woven through greenery, and spaces designed for human interaction, not cars. Its another to see a spread of photorealistic images of what that could actually look like. By creating realistic representations of imagined realities, text-to-image-generating AI can make it easier for the mind to include new possibilities in how it imagines the world, reducing the barriers to believing that they could become a lived reality.
Last Friday, Reddit user u/trippy_art_special posted the image of the pope to the Midjourney subreddit, the generative AI platform used to produce it. The post contained four variations (a hallmark of Midjourney) of the pope ensconced in an on-trend long, puffy, white coat. One even had him in dark sunglasses, which looked especially smooth, even mysterious, in contrast to the radiant white of the coat and the deep chain.
The image was widely mistaken as real, and the popes outfit was big news over the weekend. Once people caught on that the image was fake, it became even bigger news. No way am I surviving the future of technology, the American model Chrissy Teigen tweeted.
Debates over why this particular image went viral or why so many people believed it to be real will soon be moot. For something that appears so convincing, why wouldnt we believe it? Neither was this the first media brush between Pope Francis and high fashion. In 2008, the Vatican daily newspaper quashed rumors of designer loafers, stating, The pope, therefore, does not wear Prada, but Christ.
For those who scrutinized the image, you could still find clues of falsehood. A few inconspicuous smudges and blurs. But Midjourneys pace of improvement suggests correcting these remaining signs will happen swiftly. What then?
At The Verge, senior reporter James Vincent likened AI-generated imagery to the dawn of hyperreality, a concept developed by the French philosopher Jean Baudrillard. Sooner or later, Vincent wrote, AI fakes are going to become hyperreal, masking the distinction entirely between the imaginary and the real.
Its easy to imagine the nightmare that could follow. Hyperreality is usually invoked as a concern over simulations displacing reality, posing real and looming threats. AI fakes will offer fertile grounds for a new and potentially harrowing era of misinformation, rabbit holes unmoored from reality, and all manners of harassment. Adapting media literacy habits and protective regulations will be crucial.
But there is an upside: While AI fakes threaten to displace what the mind perceives as reality, they can also expand it.
In 1998, two leading philosophers Andy Clark and David Chalmers published a paper on their idea of the extended mind. They argued that cognitive processes are not confined within the boundaries of the skull, but extend out through the tools we use to interact with the world. These aids a notebook, for example are tangled up in how we think and are part of our extended minds. In this view, tools can become something like cognitive limbs: not separate from our capacities, but part of them.
You can flip this around: Building new tools is a way of building new mental capabilities. Until last weekend, most people could have imagined some image of what the pope might look like in a fashion-week puffer jacket (unless you have aphantasia, in which mental imagery is not part of your internal experience). But those mental images can be slippery. The more artistic among us could have drawn a few ideas, prompting a richer image. But soon, anyone will be able to imagine anything and render it into photorealistic quality, seeing it as though it were real. Making the visual concrete gives the mind something solid to grab hold of. That is a new trick for the extended mind.
You should understand these tools as aids to your imagination, says Tony Chemero, a professor of philosophy and psychology at the University of Cincinnati and member of the Center for Cognition, Action, and Perception. But imagining isnt something that just happens in your brain, he added. Its interacting skillfully with the world around you. The imagination is in the activity, like an architect doing sketches.
There is disagreement among cognitive scientists on which kinds of tools merge with our extended minds, and which retain separate identities as tools we think with rather than through. Chemero distinguished between tools of the extended mind, like spoons or bicycles, and computers that run generative AI software like Midjourney. When riding a bicycle and suddenly wobbling through an inconveniently placed crater in the concrete, people tend to say, I hit a pothole, instead of, The bicycle wheel hit the pothole. The tool is conceived as a part of you. Youd be less likely to say, I fell on the floor, after dropping your laptop.
Still, he told me that any tool that changes how we interact with the world also changes how we understand ourselves. Especially what we understand ourselves as being capable of, he added.
Clark and Chalmers end their paper with an unusually fun line for academic philosophy: once the hegemony of skin and skull is usurped, we may be able to see ourselves more truly as creatures of the world. Thinking with AI image generators, we may be able to see ourselves in picture-perfect quality as creatures of many different potential worlds, flush with imaginative possibilities that blend fact and fiction.
It might be that you can use this to see different possible futures, Chemero told me, to build them as a kind of image that a young person can imagine themselves as moving toward. G20 summits where all the world leaders are women; factories with warm lighting, jovial atmospheres, and flyers on how to form unions. These are now fictional realities we can see, rather than dimly imagine through flickers in the mind.
Of course, reality is real, as the world was reminded earlier this week when 86-year-old Pope Francis was taken into medical care for what the Vatican is calling a respiratory infection, though by Thursday he was reportedly improving and tweeting from the hospital. But if seeing is believing, these tools will make it easier for us to believe that an incredible diversity of worlds is possible, and to hold on to their solid images in our minds so that we can formulate goals around them. Turning imagination into reality starts with clear pictures. Now that we can generate them, we can get to work.
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What the AI-generated image of Pope Francis means for the imagination - Vox.com
By the Book: Sarah Bakewell Is No Fan of Thrillers and Mysteries – The New York Times
How do you organize your books?
Most of them are organized with sinister precision by genre and author, except that biographies are by subject and history is roughly chronological. I cant help it; Im a librarian. Not only that, but I tend to spot anomalies. If someone has moved a book out of order, I fix it with my gimlet eye almost as soon as I walk in the room. Of course, this leads to people moving my books around for fun, to see if Ill notice. (And sometimes I dont.)
Every year, I receive a book of stories, memoirs, drawings or clerihews, as well as a wall-calendar of splendid literary caricatures, all created by my generous and gifted friend in Seattle, Brad Craft. Nothing can ever beat that.
As a child I read books manically, greedily and repeatedly, and loved anything with an animal in it. My two favorite series were Willard Prices gung-ho stories about two brothers collecting wild creatures for their fathers zoo, and the Adventure series by Enid Blyton, which sent four children and a parrot into dangerous situations up a river, out to sea, inside a hollow mountain and away with a traveling circus.
By my early teens, I was grabbing any book for adults that came within my reach, and making whatever skewed, half-baked sense of it I could. Woolfs The Waves, Nabokovs Lolita, Ginsbergs Howl, Luke Rhineharts The Dice Man, David Nivens The Moons a Balloon, a bit of Shakespeare it all went into the ravenous maw. I do remember being more perplexed than usual by The Sex-Life Letters: Fascinating Correspondence From Todays Men and Women About the Variety of Their Sexual Attitudes and Experiences, edited by Harold and Ruth Greenwald. I think that had animals in it too.
Ive long liked both philosophy and biography, but the balance keeps shifting toward the biography end. In my 20s, a night in with Heidegger was my idea of fun. Now, given a choice between contemplating the being of beings and finding out, for example, that Vita Sackville-Wests mother once papered an entire room with used postage stamps well, its the stamps every time.
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By the Book: Sarah Bakewell Is No Fan of Thrillers and Mysteries - The New York Times
Human behavior and performance in deep space exploration: next … – Nature.com
The next phase of human space exploration includes the establishment and habitation of a lunar gateway, a permanent base on the Moons surface, and exploratory crewed missions to Mars. As human activity in space moves from Low Earth Orbit (LEO) operations, such as those that take place on the ISS, to deep space exploration, the crews will face a different set of psychological challenges1. These include extended mission durations, increased distance from Earth, prolonged isolation and confinement, reduced size of crew quarters, lack of privacy, communication latency, need for increased autonomy in decision-making processes, and lack of short-term rescue possibilities, amongst other known and as yet unknown demands2,3.
There is good evidence to suggest that astronauts behavior, health, and performance can be impacted by the demands encountered in future space missions4. For the purposes of this work, issues of behavior, health, and performance are separated and considered according to discrete cognitive, affective, behavioral, social, and mental health components. While these function areas are related, distinguishing between them provides the opportunity for conducting well-specified and targeted psychological studies. Cognitive dimensions include issues of perception, vigilance, judgment, memory, and reaction time, amongst other executive functions5. When discussing cognition, there are clear synergies with the neurosciences. Affective experiences refer to emotions, feelings, and moods, which can be shaped by a persons physiology and subjective experience. Behaviors include observable individual and interpersonal actions and the execution of skilled performances. For instance, before they are executed, motor actions must be planned in the brain and rely on complex neuronal networks. Team-level social functions include relevant team process dynamics, such as experiences of cohesion and conflict. Mental health is a relevant component, which is related to the psychosocial, affective, cognitive, emotional, and physical challenges that astronauts face during missions. Mental health includes the importance of managing psychophysical stress and promoting well-being, both on individual and team levels.
This white paper is the result of a consensus among experts invited by the European Space Agency to update the roadmap for scientific research for the next decade6. The psychology working group (corresponding to the authors of this paper) was composed of experts in psychological science with a large research experience in the space context, currently engaged in research with ESA, in the space environment, analogue environments, and ground-based research. Research gaps were identified by the experts, referring to their direct research experience and to their knowledge of the scientific literature, and discussed to reach a consensus. The work specifically focused on the behavioral and performance aspects. Some of the relevant aspects that could impact the astronauts life, including the effects of space radiations, were not addressed by this group, as they have been included in other working groups report.
In this report, we broadly refer to long-duration (i.e., >30 days) space exploration (LDSE) missions, with a particular focus on deep space voyages, outside the earths atmosphere, which are distinct from current long missions in LEO. Even with this differentiation, it is worth keeping in mind that the psychological challenges of relatively near-Earth explorations, including incoming Moon missions, may be qualitatively different from those that will be experienced during long-distance deep space voyages, such as human missions to Marswhich also include long travels and an extreme routine. In the following, many of the open questions related to psychological function in space are framed in the context of LDSE missions. However, where we refer to space missions broadly, questions are pertinent to LEO, lunar and deep space missions. With respect to an understanding of human performance and behavior issues of spaceflight, the European Space Agency and its partners can build on several years of studies and experiences on the ISS and sub-orbital flights, as well as during simulations studies and in analogue environments. Deep space exploration, though, has some different characteristics that will require ad-hoc preparation and new studies to answer currently open questions. For this reason, further studies will be needed not only to be conducted during long-duration space missions, but also in other settings, including analogue environments and other isolated and confined settings. These environments share some similarities with the space context, including isolation and confinement. Some analogue missions are conducted in specifically designed facilities, such as HERA (Human Exploration Research Analog), the underwater research station NEEMO (NASA Extreme Environment Mission Operations), and the MARS500 isolation chamber. Other facilities include Antarctic stations, such as the Concordia base, an Italian/French research facility considered one of the most remote outposts on Earth. Most of these environments allow to study behavioral, physical, and team dynamics, and to test countermeasures that can be implemented in space missions. Other analogue environments allow to recreate specific challenges of space research, including radiations (e.g., the NASA Space Radiation Lab) and bedrest implications (e.g., the: envihab facility, in Cologne, Germany).
Risks to behavior, health, and performance during deep space exploration could be mitigated and astronaut function optimized with the application of effective countermeasures. However, research is required to identify and further develop or refine the strategies and approaches that might be used to enable astronauts to maintain elevated well-being and high-performance standards on LDSE missions. In the following section, we distinguish between questions related to basic issues of adaptation and countermeasures. The former largely deals with the understanding of psychological aspects of deep space exploration and the impact of unique deep space mission demands upon behavior, health, and performance. This includes the role of individual differences in adaptation, and broader mechanisms underlying individual and team phenomena that are relevant to human spaceflight7,8,9. Important information in this area could be inferred from different types of observational and correlational studies. Countermeasures deal with the specific actions and interventions that space agencies can enact to mitigate the risks of future missions. This might include a refined selection process or the application of inflight psychological training and support. While most questions in the white paper focus on pre-mission and inflight activities, it is also important to consider psychological experiences in the post-mission phase, to ensure that astronauts well-being is robust after the end of what are likely to be physically and psychologically demanding voyages. Astronauts constitute a very limited community on Earth. When addressing these fundamental questions, it is therefore critical to consider whether and how the findings can be transferred to the general public as many activities parallel, to some extent, what space travelers will undergo.
Most knowledge in space psychology has focused on short-duration mission, relatively close to Earth, and with synchronous contacts with mission control. New incoming space missions pose different challenges, in terms of psychological adaptation and the definition of countermeasures to mitigate risks.
To inform the identification of effective preparatory and preventative countermeasures for future space missions, there are several questions related to basic issues of psychological adaptation that need to be resolved. These questions relate to both in-mission dynamics influenced by the interaction between individual and team factors and contextual demands, and what happens in the post-mission phase. Open questions identified by the expert scientific group, largely reflect unknowns associated with missions beyond Low Earth Orbit (LEO).
For the ISS, there already exists a standard human behavior and performance competency framework for crewmembers10. There have also been efforts to standardize the psychological/psychosocial and behavioral data collected during space agency sponsored research activities11,12,13. This research has been used in ground-based studies in analogue environments, such as NASA-HERA, VaPER, AGBRESA, SIRIUS 19 & 20, as well as Antarctica. Standard measures have been used on the International Space Station in multiple expeditions14. These standard measures have included cognition batteries, personality surveys, and neuroscience assessments of sensorimotor measures, together with biomarkers, immune markers, and actigraphy. All these data will help create useful benchmarks for LDSE missions. Nevertheless, despite the important research and the progress made so far, there is a need to continue this research in analog environment and long-term spaceflight. In addition, the scope of this research should be enlarged with respect to including also physiological measures as possible indicators of mental health and performance state, as well as measures of team cohesion and climate which can capture team dynamics in the course of LDSE missions. Questions that must be addressed include:
What variables capture relevant information on cognitive, affective, behavioral function, and team functions? And what outcomes are informative about mental health issues?
What physiological biomarkers provide a valid insight to the psychological experience of astronauts?
To date, there have been many studies on spaceflight stressors that have utilized both space platforms and ground-based analogs. However, for LDSE missions the type and magnitude of stressors encountered will be different from those experienced in the past. Research is needed to evaluate the impact of such stressors on individual and team function. Certain stressors could be evaluated in analog environments (e.g., isolation, confinement, chronic threat, sleep deprivation, sensory deprivation), while the effects of others will need to be examined in space (microgravity, hypogravity). Research conducted during spaceflight, in analog environments and simulation studies, thus far, has already provided important insights into the effects of microgravity, prolonged confinement, and isolation, as well as sleep deprivation on human performance, well-being, and behavior15. However, the impact of stressors such as prolonged hypogravity, transitions between different levels of hypogravity, prolonged radiation exposure, chronic threat due to lacking rescue possibilities, extreme levels of crew autonomy, and Earth-out-of-view unique to LDSE missions, have not been addressed yet, or only to a very limited degree (e.g., effects of autonomy during simulation studies)16,17. Their impact on cognition, affective experiences, behavior and performance, team dynamics, mental health, and performance should be carefully assessed. Some of these stressors can be studied in analog environments (e.g., autonomy), others require spaceflight experiments during upcoming missions to the Moon (e.g., hypogravity) and still others might be only investigated during actual LDSE missions (e.g., Earth-out-of-view effects). Moreover, the relationship among stress biomarker dynamics (e.g., heart rate variability, cortisol), related biological processes, and individual and team function within these settings will have to be clearly unfolded.
While there have been many studies on individual differences in relation to human spaceflight, data that exist remains relatively limited in a predictive sense1. Additional research is needed to examine how baseline individual and team characteristics are likely to impact upon in-mission individual and team function. Moreover, day-to-day team performance indicators need further exploration in the context of extreme environments.
How do demographic criteria (e.g., age, gender identity, and ethnicity) influence adaptability and individual function during space missions?
What is the unique impact of sexuality on the psychological function of crewmembers in space?
How do individual psychological differences (e.g., personality, motivation, and values) influence adaptability and individual and team function during space missions?
What individual difference factors should be used to inform effective team composition decisions for LDSE missions?
How do team structure and composition influence crew adaptability and function during space missions?
How do social dynamics, values, norms, and culture influence crew adaptability and function during space missions?
How can we assess team performance and dynamics on a small scale, and how does that relate to the overall mission success?
The high levels of autonomy that will be encountered on LDSE missions mean that crew will have increased responsibility for their own self-care/self-management18. New research is needed to examine the coping and health and performance self-regulation strategies that individuals and teams use to maintain their function. Although there have been initial studies on coping in analog settings19, there is limited empirical data on what astronauts do to manage themselves and their teams during space missions (LDSE or otherwise). Open questions are:
What resources and equipment (e.g., food variety, entertainment systems) contribute to effective coping and self-regulation during LDSE missions?
What coping and regulatory strategies are effective for optimizing cognition, affective experiences, behavior and performance, individual and team function, and, more in general, to promote mental health during LDSE missions?
Integrative studies that examine the interactive effects of psychosocial factors alongside physiological responses and other features of the environment, such as habitat design and resource availability, are required to provide a deeper insight to the human experience in space. This is especially important for LDSE where new systems, equipment, and habitats will be used. Among the unanswered questions, we find:
How do spaceflight stressors, demographic criteria, individual differences, coping, and regulatory strategies interact to impact individual and team function during LDSE missions?
What factors predict the extent to which skill fade occurs during LDSE missions?
How do physical features of the environment (e.g., habitat, architecture, internal conditions, and plants) impact upon individual and team adaptation?
How do food perception (e.g., taste and olfaction), texture, and variety impact upon astronauts affective, experiences?
How do astronauts interact with reporting systems designed to capture safety-critical information (e.g., medication use)?
What individual and team factors impact upon compliance with reporting systems designed to capture safety-critical information (e.g., medication use)?
The post-mission phase has addressed by research one both overwinter missions in Antarctica (e.g., ref. 20), and NASA post-flight standard measures14. However, it still requires a structured and deepened exploration, which has been sometimes overlooked. Anecdotal reports from the astronauts of the lunar missions in the 1960ies and 70ies suggest, that the mental processing of such extreme experiences represents a challenge also after the actual mission. With LDSE missions, the importance of questions related to reintegration, recovery, and mental processing of the mission experiences will significantly raise. Specifically, crucial open questions which need to become addressed more systematically relate to what positive or negative after-effects might occur after prolonged spaceflights, and what regulatory strategies might be effective to support reintegration, recovery, and rehabilitation upon return from LDSE missions. For example, there is limited empirical information on how individuals cope during their return from space and what strategies they use to maintain their health and well-being during reintegration and recovery. Research is needed to identify the strategies that individuals use and what impact that has upon their cognition, affect, and behavior in the post-mission phase. Open questions include:
What individual coping and regulatory strategies are effective for optimizing cognition, affective experiences, behavior, and performance, and, more in general, mental health, during the return, transition, and recovery following LDSE missions?
How do social networks contribute to effective astronaut coping and self-regulation during their return?
How do individuals prepare themselves and their families to redeploy on new missions?
Addressing open questions related to basic issues of adaptation should provide the knowledge to develop effective countermeasures for the envisaged future space missions. Psychological countermeasures might target selection and training, in-mission, and post-mission phases. The emphasis in this white paper is on identification and testing and evaluating the impact of applied measures.
Current selection and training protocols have been designed for LEO missions. Research is needed to identify how individual and team psychological selection should be adapted for LDSE missions. Specifying and developing the training needed to ensure optimal crew function on LDSE is also needed. While existing processes might continue to have utility, this should be confirmed with empirical evidence. Questions that still have to be addressed include:
What individual difference factors inform on psychological suitability for LDSE missions?
How should psychological suitability be assessed during the assessment and selection of astronauts for LDSE missions?
What methods are available to inform the selection of psychologically compatible or incompatible teams?
Do these methods raise any ethical concerns?
How should current selection processes be adapted and validated to inform the effective psychological selection of crewmembers for LDSE missions?
What unique training protocols need to be developed and how should they be delivered (e.g., what strategies, tools, and techniques) to prepare individuals and teams to respond effectively to the demands of LDSE missions?
How should individuals and teams be trained to respond effectively to critical or off-nominal incidents when operating autonomously in space? What protocols and policies need to be developed?
How should approaches and methods for optimizing affective experiences and cognition (e.g., mind-body strategies, emotion regulation, and flexible coping) during space missions be trained?
How should approaches and methods for optimizing team function (e.g., communication, cooperation, collaboration, and conflict resolution) during space missions be trained?
How should astronauts be trained to deal with extreme and unexpected events (e.g., deaths and psychiatric issues) that might occur during LDSE missions?
Support during and after LDSE missions will rely on accurate monitoring, diagnosis, and deployment of effective countermeasures. Although research in these areas is currently being undertaken, there remain a number of open questions about how to best support individuals and teams in space. Studies conducted in microgravity and on ground-based analogs can be used to identify and evaluate the efficacy of approaches to support individuals and crew during and after return from LDSE missions.
What methods, measures, and metrics should be used to monitor individual and team function, sleep, and fatigue during space missions?
How should work/life balance be managed during different phases of a LDSE mission?
How can astronauts be supported and what resources do they need to allow them to rest and relax away from work tasks?
How should sleep and fatigue management skills for LDSE missions be trained and maintained?
What non-pharmaceutical approaches are effective for sleep and fatigue management during LDSE missions?
How should methods used to minimize skill fade and degradations in task performance during LDSE missions be administered?
How should astronauts be supported to maintain their motivation to engage in healthy behaviors (e.g., exercise) across the duration of a LDSE mission?
What and how should support be provided following the occurrence of extreme and unexpected events (e.g., deaths and psychiatric issues)?
How should approaches and methods for optimizing mental health, affective experiences, cognition, behavior, and performance (e.g., mind-body strategies, emotion regulation, and flexible coping) during space missions be maintained?
How should approaches and methods for optimizing team function (e.g., communication, cooperation, collaboration, and conflict resolution) during space missions be maintained?
How should autonomous and digital systems be used to effectively support individual and team functions during LDSE missions?
How do human factors impact upon autonomous and digital system interaction?
What features must be included in autonomous and digital systems for effective use in space?
How do trust and privacy impact the likelihood of astronauts engaging with autonomous and digitally delivered countermeasures?
What communication types/methods are effective as a mechanism for support during autonomous missions?
How should communications be adapted to effectively support team function during autonomous LDSE missions?
What family support mechanisms need to be established to minimize potential issues due to separation and lack of family contact during LDSE missions and what would be the optimal communication frequency and duration?
How should families and social groups be effectively-prepared to support those returning from space?
Psychosocial function of astronauts can be impacted by the system that the individual and team are operating in. The constraints of LDSE missions mean that new systems, architectures, and habitats will need to be developed. There are open questions about how to engineer and design the systems, architectures, and habitats to facilitate optimal function in space:
How should autonomous and digital systems be designed for use during LDSE missions? In particular, what would be the benefits of using virtual reality-based approaches?
How should communications be designed to effectively support individual functions during autonomous LDSE missions?
What architectural and habitat design features should be implemented to enhance individual and interpersonal function during LDSE missions?
What features should be considered and designed into safety-critical reporting systems (e.g., medication reporting systems)?
How might an astronauts connection to nature be established through architecture and habitat design?
Several of the identified knowledge gaps have direct relevance for micro- and hypogravity research. In particular, this holds true for a better understanding of the effects of hypogravity on human cognition and performance, which are already relatively well understood for some basic cognitive functions, but which lack knowledge with respect to higher executive functions or issues related to skill maintenance across different levels of (hypo-)gravity. The clear majority of the key knowledge gaps previously identified, however, relate to basic issues of individual or crew adaptation to long-term confinement and isolation and to effective countermeasures for maintaining well-being and performance of crews under such conditions. To close these knowledge gaps is of most relevance for future exploration missions to the Moon and Mars which will involve more extreme conditions of isolation and confinement than has been known from other environments, thus far. Even though the conditions of travel to the Moon will be more extreme than what we know from near-Earth orbital spaceflight and overwintering in Antarctica, they do not seem to be different in a qualitative sense (i.e., the demands are amplified rather than being especially unique). Thus, it might be expected that at least some of the current knowledge about the psychological effects of isolation and confinement as well as hypogravity might be generalized to missions in lunar orbits or even stays on the lunar surface. In contrast, future deep space missions to Mars will represent a qualitatively much more extreme change (e.g., with respect to autonomy, restricted means of crew-ground communication, lack of evacuation possibilities) compared to what has been known about effects of isolation and confinement from other fields already, and, thus, will provide completely new psychological challenges which currently are not well understood. In a sense, future missions to Mars will resemble past ambitious naval explorations, such as those conducted by Vespucci and Colombo, in which humans pushed their limits beyond a line that had never been crossed before21. However, on the other hand, we are arguably more prepared than a crew on a ship that did not know what they were about to find, as, we can prepare such missions using probes, satellites, and many other remote observation techniques. Among the preparation activity, psychological research addressing the knowledge identified gaps will be a fundamental step in any space program focusing on exploratory human missions to Mars and beyond. While microgravity and hypogravity pose serious challenges to the central nervous system22, most of the knowledge gaps about behavioral and psychological aspects are not related. Therefore, the research needed does not necessarily involve research during actual space missions. Naturalistically extreme environments on Earth (e.g., Antarctica) and, even better with respect to experimental control, simulation studies on the ground will, in many cases, provide appropriate environments for such research.
The research gaps highlighted in this report are in line with the ones identified by NASA23. The need to identify and validate countermeasures to promote health and performance, to define improved monitoring and assessment strategies, and to investigate and optimize team dynamics, for example, are shared concerns between this report and the NASAs Evidence Book for Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders23. Similar conclusions have been described in a recent NASA report24 about team research, highlighting the lack of data availability from the space context, and the need for further research on the topic, including studies in analogue environments and subject matter expert interviews.
Space travels magnify the challenges posed to a team of astronauts, such as confinement, and lack of external communication. However, there are also many situations that regular workers can face on the Earth and that includealthough to a lesser extent, some features astronauts can meet. For example, teams sometimes work in remote places, where communication is constrained. Therefore, more classical Earth-based activities can benefit from the transfer of this fundamental research.
Research conducted to fill knowledge gaps identified in the psychological phenomenon linked to space exploration may be applied to optimize the behavior, health, and performance of crewmembers in these extreme conditions. Once the processes that might contribute to the possible impairment have been identified, it could be envisaged to elaborate specific countermeasures that could help crewmembers to maintain and enhance their health and performance. For example, innovative and new technologies like virtual reality may be stimulated by this kind of challenge and be used to provide sensory stimulation and train cognitive and psychomotor performance of crew without there being a requirement to undertake live operations. New technologies (e.g., artificial intelligence) may also be used to reduce communication delays and, thus, mitigate isolation consequences.
As frequently observed with space research, many new devices, technology, or stress management techniques, may, once tested in space, be efficiently applied to adaptation and performance on Earth in specific conditions. For example, during the sanitary crisis period, some results concerning adaptation to isolation and confinement obtained in space or in polar environments have been useful for people during confinement periods. Some operational or mental strategies identified and validated in space may be transferred to life on Earth in isolation, confined, and extreme conditions. In many instances, this might be in settings that have societal important e.g., climate scientists, defense and security personnel, and anti-poaching wildlife rangers. Since constraints on the design of such techniques can be largely relaxed for Earth applications compared to Space applications, more flexibility is a promise for wider applications for the public. Finally, the space brand exerts great charm on the public and can be a channel for the promotion of societal and psychological improvements. For example, pro-environment behaviors studied and reported by the astronauts may be mimicked on Earth; well-being promotion strategies that are currently developed for space explorations, such as certain mind-body techniques, can also be implemented on the planet, following the examples from the space context. There are therefore several environments in which behavioral space research can have a positive impact on Earth research and society, including educational, organizational, professional, and recreational contexts. To facilitate these benefits, the communication strategy implemented by all the involved actors (national agencies, private companies, astronauts) should be mindful of these potential implications.
Table 1 reports the overarching categories representing the key open psychological research questions related to lunar and LDSE missions. Many of the open questions could be partly addressed in ground-based analogs. However, where the unique demands of missions beyond LEO and in deep space are relevant, ongoing research across various platforms will be needed. To effectively prepare for future LDSE missions, such as a Mars expedition, we suggest these questions should be addressed during a short to medium timeframe. There are certain unknowns that will only be elucidated over longer time periods and perhaps during a Mars mission itself. We recommend these timelines (3, 5, and 10 years) as a suggestion for addressing research gaps, although we are aware that research often requires longer times, so they do not necessarily correspond to expected research results.
The countermeasures below have all been used to mitigate the psychological demands of spaceflight. However, beyond a few initial studies, there has been a relatively limited attempt to empirically test the impact of their application (see Table 2). Before these methods can be considered evidence-based further space and/or analog-based research would be needed.
This white paper reported the results of a consensus statement among experts invited by ESA about the existing knowledge gaps on behavioral and performance topics of space research. This is particularly timely, as exploration missions are moving from low orbit to deep space destinations, with new psychological and team challenges forthcoming. While this is a non-systematic review of these research gaps, the working group consisted of experts in space psychology, who have been engaged in space research for ESA. Pre-, during-, and post-mission challenges and research gaps were considered, referring to promising countermeasures, either with preliminary evidence of their effectiveness, or to be developed and tested. The results summarize a set of challenges and questions to be addressed, but also some potential answers that have already been provided by the scientific community over decades of space psychology research. New empirical evidence is required to address most of these gaps, collected with specifically designed studies. It must be noted that to address the contextual constraints (e.g., number of active astronauts, or available analogue environment), some of these gaps can be tackled with thorough reviews or white papers incorporating all extant research findings. While space psychology is likely to have an important future, researchers should also be mindful of previously developed knowledge.
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Human behavior and performance in deep space exploration: next ... - Nature.com
[VIDEO] Terrifying Tree Well Rescue Highlights Why You Should … – SnowBrains
Terrifying.Its one of those superlatives websites use to get you to click. But in this case, its justified. Its terrifying to think how quickly your day can change from shredding deep powder and having the time of your life to actually fighting for your life. Its terrifying to imagine the thoughts going through that boarders mind. Its terrifying to think what would have happened had that skier not been in the right place at the right time. Terrifying.
I just watched this twice, astonished by how lucky to be alive the snowboarder is. Both men were riding through trees in the Mount Baker, WA, sidecountry in extremely deep snow, and its pure serendipity that the rescuer skied over the buried boarder.
Despite finding myself urging the skier to move quicker while watching, he does everything right and saves this strangers life. I cant imagine what was going through the boarders mindhe was rendered immobile by his powdery tomb.
Thank you to Francis Zuber for sharing this video, being in the right place at the right time, and for an expert rescue.
Tree well and deep snow suffocation are serious problems in the Western USA and Canada.
Incidents occur with deep snow accumulations and tree well immersions, where a skier orsnowboarder falls into an area of deep, unconsolidated snow and becomes immobilized.
Since 2001, California has had more snow immersion deaths than any other state.
A tree well is a void or depression that forms around the base of a tree and most likely under thebranches that hang from those trees, disguising the void. This void may contain a mix of low-hangingbranches, loose snow, and air. While skiing or snowboarding, it is tough to determine if a treewell exists, so skiers and riders should treat every tree the same.
Skiers and snowboarders must understand the risks of deep snow, educate themselves, and strictlyadhere to safety recommendations, including always skiing or riding within sight of a partner, especiallywhen off a designated trail, within the trees, or in a gladed area.
Tree Well Fall. Image: Ski California
Each skier or snowboarder controls their level of risk. Only you can preventthis type of accident from happening. To minimize your risk, you must know how to travel safely with your partner(s) in theseungroomed deep-snow areas. Always ski or ride with a partner and within close sight.
Always stay in visual contact so your partner(s) can see you if you fall. Visualcontact means stopping and watching your partner descend at all times, then proceedingdownhill while they watch you at all times. It does no good if your partner is alreadywaiting for you in the lift line while still descending the slope.
Stay close enough to either pull or dig out. Hold your breath while reading this if you have questions about what is close enough to assist someone in a tree well. The time before your partner needs air may be how long you have to pull or dig the person out of danger. Other factors, such as creating an air pocket or the entrapped skiers position, may also affect this critical timeframe.
Remember, if you lose visual contact with your partner, you could lose your friend. It is essential to know that most people who have died in deep snow or tree well accidents had been skiing or riding with a partner at the time of their accident. Unfortunately, none of these partners had immediate visual contact, so they could not help promptly.
Use appropriate equipment to minimize risks. When skiing or snowboarding in high-risk areas for deep snow or tree wells, wear a helmet, enter the ski patrols phone number into your smartphone, and carry a whistle if you need to get someones attention if you become entrapped in deep snow or a tree well.
If you still have questions, contact your ski patrol. Ask your ski patrol about the current risks and conditions with deep snow at your local ski area before you explore risky terrainsuch as tree areas, glades, or off-trail terrain where deep snow and tree well risksexist.
Follow these helpful tips to stay safe on the Mountain. All the recent snowfall in California, Utah, and the west, along with more in the forecast, makes for dangerous conditions, so always take necessary precautions and never venture out alone.Stay Safe Out There. Image: Ski California
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[VIDEO] Terrifying Tree Well Rescue Highlights Why You Should ... - SnowBrains
Who’s schooling Congress on AI? – Axios
Congress gets a lot of flak for not being savvy on tech issues. But as artificial intelligence advancements heat up, some members are working hard to educate themselves.
Why it matters: AI has the potential to transform our society, and as lawmakers grapple with how to regulate the technology, companies are scrambling to inform their opinions.
Behind the scenes: Generative AI is heavy on lawmakers' minds on both sides of the aisle. Here's some of what we're hearing has been happening:
CEOs on the Hill: Sen. Mark Warner has met with OpenAI CEO Sam Altman and Scale AI CEO Alexandr Wang along with Tristan Harris, executive director of the Center for Humane Technology, per spokesperson Rachel Cohen.
What they're saying: We believe AI may represent the most consequential technology advancement of our lifetime. There is enormous interest in the opportunity ahead. And responsibilities for those of us who develop this technology. Were using this time to educate, be curious, and learn, a Microsoft spokesperson told Axios.
Threat level: Christopher Padilla, IBM's government and regulatory affairs vice president, said he worries there will be a techlash" and emphasized that consumer-facing AI, such as ChatGPT, brings about fundamentally different risks from the AI work his own company is doing.
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Who's schooling Congress on AI? - Axios
2023 CANADA GAIRDNER AWARDS RECOGNIZE WORLD-RENOWNED SCIENTISTS FOR TRANSFORMATIVE CONTRIBUTIONS TO RESEARCH IMPACTING HUMAN HEALTH – Yahoo Finance
TORONTO, March 30, 2023 /CNW/ - The Gairdner Foundation is pleased to announce the 2023 Canada Gairdner Award laureates, recognizing some of the world's most significant biomedical and global health research and discoveries.
Gairdner Les Prix Canada Gairdner Awards (CNW Group/Gairdner Foundation)
"Congratulations to all the 2023 Canada Gairdner Award recipients! The ground-breaking work of this year's laureates has resulted in innovative, globally accessible tools to fight diseases and improve our well-being. The work of two Canadian researchers Dr. Christopher Mushquash and Dr. Gelareh Zadeh especially stands out. Dr. Zadeh's research to better understand brain tumours and Dr. Mushquash's research on Indigenous-led mental health and substance use will be transformative in improving the quality of life of so many here in Canada and around the world."
- The Honourable Jean-Yves Duclos, Minister of Health
"Our government knows that in order to create a better future for all, we need to foster the research that will improve human health around the globe. It is why I want to congratulate the 2023 Canada Gairdner Awards recipients showcasing international excellence in science and research. I'm proud to highlight the two Canadians awarded for their world-class achievements including improving our understanding of brain tumour treatments and providing culturally appropriate mental health services for First Nations."
- The Honourable Franois-Philippe Champagne, Minister of Innovation, Science and Industry
"I wish to congratulate this year's award recipients for their groundbreaking research and the profound contributions that their discoveries will have. It is specifically noteworthy to see Dr Christopher Mushquash as a recipient of the 2023 Canada Gairdner Momentum Award. Chris's contributions to our understanding of mental health amongst Indigenous communities are already profoundly affecting the needs of Indigenous peoples. As a member of CIHR's Institute for Indigenous Peoples Health Advisory Board, Chris has provided the same critical thinking to advancing Indigenous research in Canada."
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- Dr. Michael J. Strong, President of the Canadian Institutes of Health Research
2023 Canada Gairdner International AwardThe five 2023 Canada Gairdner International Award laureates are recognized for seminal discoveries or contributions to biomedical science:
Demis Hassabis, CBE FRS FREng FRSA
Founder & CEO, DeepMind; Founder & CEO, Isomorphic Labs
John Jumper, PhD, MPhil
AlphaFold Lead and Senior Staff Research Scientist, DeepMind
Awarded "For developing AlphaFold, which has been heralded as an AI-based solution to the 50-year grand challenge of protein structure prediction and has culminated in the release of the most accurate and complete picture of the structure of the proteome, with enormous potential to accelerate biological and medical research."
The Work:
Proteins are essential to life, supporting practically all its functions. They are large complex molecules, made up of chains of amino acids, and what a protein does largely depends on its unique 3D structure. Figuring out what shapes proteins fold into from their amino acid sequence is known as the 'protein structure prediction problem' and has stood as a grand challenge in biology for the past 50 years. With their team at DeepMind, Demis Hassabis and John Jumper have developed the artificial intelligence (AI) system AlphaFold, which today can predict the structure of a protein, at scale and in minutes, down to atomic accuracy.
Hassabis had long suspected that protein structure prediction might be the perfect problem for AI to tackle. He was the project leader on the AlphaFold project from its inception in 2016 to its conclusion, and recruited Jumper to the project in late 2017. In 2018 the team was expanded, with Jumper becoming the new research lead, with the goal to re-design the system with a completely new architecture into what would become AlphaFold2. Together they co-supervised the subsequent projects to create the most accurate and complete picture of the human proteome and predict the structures of nearly all known proteins, and released an open-access database to make all of AlphaFold's predictions freely available to the scientific community.
In a major scientific advance, in 2020 AlphaFold2 was recognized as a solution to the 50-year grand challenge of protein structure prediction by the organizers of the biennial Critical Assessment of Protein Structure Prediction (CASP).
The Impact:
AlphaFold has culminated in the creation of structure predictions for over 200 million proteins - nearly every protein known to science - which DeepMind have made freely available through the AlphaFold Protein Structure Database (AlphaFold DB).
Designed in partnership with European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), the AlphaFold DB serves as a 'google search' for protein structures, providing researchers with instant access to predicted models of the proteins they're studying, which has the potential to accelerate every field of study in biology.
Since launch, the AlphaFold DB has already been accessed by 1 million researchers and users in 190 countries. The program dramatically reduces the time scientists typically spend determining protein structure and demonstrates the impact AI can have on scientific discovery and its potential to accelerate progress in some of the most fundamental fields that explain and shape our world. Further, this research will help to better our understanding of disease, and accelerate the development of new targeted drugs.
Bonnie L. Bassler, PhDSquibb Professor and Chair, Department of Molecular Biology, Princeton University; Howard Hughes Medical Institute Investigator
E Peter Greenberg, PhDEugene and Martha Nester Endowed Professor of Microbiology, Department of Microbiology and Molecular & Cellular Biology Program, University of Washington School of Medicine
Michael R. Silverman, PhDEmeritus Investigator, The Agouron Institute; Emeritus Adjunct Professor, Scripps Institution of Oceanography
Awarded "For their discoveries of how bacteria communicate with each other and surrounding non-bacterial cells, providing a new paradigm for how microbes behave and yielding novel avenues for therapeutics against infectious diseases."
The Work:
Bacteria are found everywhere from soil to water to the human body. Despite their simple single-cell forms, bacteria are sophisticated organisms that are remarkably adaptable to changing conditions. Bacteria play crucial roles in medicine, both as members of the microbiome, increasingly understood to contribute to human health, and as major causes of disease. The discovery of how bacteria communicate with one another, coined "quorum sensing" by Dr. Greenberg and his colleagues, is foundational. Drs. Bassler, Greenberg and Silverman are awarded for a combined body of work that spawned an unexpected field in microbiology and are also recognized for their individual discoveries that underpin its implications for all of biology, human health and disease.
Quorum-sensing studies began with an obscure bioluminescent marine bacterium called Vibrio fischeri. In the 1970s, Dr. J. Woodland Hastings and colleagues described a signaling chemical of then unknown structure that stimulated collective glowing after the Vibrio fischeri bacteria had reached a particular population density. This finding was one of the first clues that bacteria could communicate using chemical "words", but it lay dormant for a decade until Silverman, exploiting the power of genetics, identified the genes involved in this signaling pathway and characterized their functions. Silverman's elegant analyses of the role each component played provided the world's first quorum-sensing circuit and the foundation for thousands of similar circuits identified later.
Widely thought to be a function specific to Vibrio fischeri, this phenomenon did not initially gain much traction. Indeed, the idea that bacteria could communicate was deemed highly improbable. But Greenberg was intrigued and trained with Hastings before he later independently further characterized the genes Silverman had identified, and discovered a similar quorum sensing signal that controlled virulence in the pathogenic bacterium Pseudomonas aeruginosa. The term "quorum sensing" was born as he demonstrated that this phenomenon was indeed bacterial communication, and not isolated to Vibrio fischeri. He not only showed that other bacteria exhibited quorum sensing, but he also discovered nearly all major steps in its mechanism.
It was Bassler who then brought Hastings' and Silverman's findings to an unprecedented level by showing that quorum sensing is not an exception but the rule in the bacterial world. What's more, the principal reason bacteria are so successful is that they rarely act alone. Quorum sensing turns out to be essential to many aspects of bacterial virulence and antimicrobial resistance. Initially with Silverman then later independently, Bassler discovered entirely new types of quorum-sensing signal molecules, mechanisms of detection and response to those molecules, and the profound influence quorum sensing exerts over the behaviour of many bacterial species. Moving to the human health front, Bassler demonstrated that it was possible to hijack quorum-sensing mechanisms to control virulence in globally important pathogens. She also made the stunning discovery that quorum-sensing communication is not restricted to bacteria. She found that bacteria can communicate across species and, moreover, quorum sensing underlies bacterial interactions with viruses and other types of cells. For example, she showed that human gut cells use quorum sensing to communicate with resident microbiome bacteria to defend the body against invading pathogens.
The Impact:
A new field of microbiology has emerged and the discoveries of Bassler, Greenberg and Silverman are at the heart of it, shaping and defining the field we now know as quorum sensing. They have independently and collaboratively revolutionized the way we think about bacteria, completely overturning the paradigm that bacteria act independently of each other.
The originality and elegance of their work led to novel and unexpected discoveries in the field time again, laying the groundwork for a deeper understanding of the microbial world with clinical ramifications that are being realized today. For example, Greenberg's work showed promise in targeting difficult infections such as those associated with cystic fibrosis and Bassler's small-molecule therapies are much less vulnerable to development of antimicrobial resistance than are traditional antibiotics because her strategies target the quorum-sensing mechanism rather than bacterial growth. With the recent recognition that microbes are foundational to the vitality of all corners of the biosphere, understanding their biology is crucial. Bassler's work in particular has provided vital mechanistic underpinnings that foster a growing understanding of the human microbiome, the niches in which different organisms thrive, and how behavior and competition within these niches is affected during disease.
All of this serves as pivotal in understanding how the microbiome influences our health and wellbeing and provides insight into novel ways to harness microbial communities to promote health and prevent disease. Bassler, Greenberg and Silverman have undoubtedly paved the way for unprecedented new possibilities for biological solutions to the world's most pressing problems in health, food, energy, and the environment.
2023 John Dirks Canada Gairdner Global Health Award
The 2023 John Dirks Canada Gairdner Global Health Award laureate is recognized for outstanding achievements in global health research:
Jos Belizn, MD, PhD
Senior Scientist, Department of Research in Maternal and Child Health, Institute for Clinical Effectiveness and Health Policy (IECS) Argentina; Superior Researcher at the National Scientific and Technical Research Council of Argentina (CONICET); Researcher, Bone Biology Laboratory, School of Medicine, University of Rosario, Argentina.
Awarded "For the development of innovative, evidence-based and low-cost global interventions in maternal and child health during the perinatal period that improve wellbeing and care during pregnancy, reduce morbidity and mortality, and promote equity in vulnerable populations."
The Work:
Dr. Jos Belizn is a trailblazer in the field of maternal and child health research in Latin America and internationally, focused on the perinatal period and its relevance to community health and the life cycle. His work spans basic research to international clinical studies, demonstrating the full cycle of scientific effort and leading to innovative, evidence-based and low-cost interventions. These interventions promote equity by improving maternal and child health in vulnerable populations. Through his work within these communities, he educates and empowers pregnant people, and witnesses real life health problems, which informs his outstanding scientific contributions.
Dr. Belizn discovered the connection between calcium intake and a decrease in the risk of hypertensive disorders of pregnancy (HDP) by observing Guatemalan Mayan women, where the prevalence of HDP was low, and their traditional cooking methods. Taking his observations further, he led numerous animal and human studies to confirm the association and basic studies to explain the mechanisms. He then planned and implemented international clinical trials in underdeveloped and developed country settings, which led to policy formulations at the highest international level and grassroots efforts to improve adherence to these guidelines.
This is just one of many examples of his extensive and comprehensive work to improve the wellbeing and care of people during pregnancy and interventions to reduce severe maternal morbidity and mortality. Dr. Belizn was the first to document, as well as design, test and implement landmark interventions addressing the issue of unnecessary increased use of Caesarean section. This is a complex and multifactorial challenge affecting not only high-income but also low- and middle-income countries, where associated risks can extend many years beyond delivery and are higher in those with limited access to comprehensive obstetric care. His research has also led to the decrease in unnecessary routine episiotomy worldwide, including in Canada and the US.
The Impact:
Dr. Belizn has undoubtedly improved maternal and childbirth outcomes and made a difference in the lives of pregnant people and their children. His discovery of the importance of calcium intake alone has significant potential as three billion people lack access to adequate calcium intake worldwide. Reaching the scientific community, health systems decision-makers, international organizations, practitioners, health-care providers and local communities, he has overturned practices, introduced more effective and equitable practices, and spearheaded global policies that will contribute to more equitable societies. His work has informed various World Health Organization recommendations, which have been adopted by many countries around the world. Dr. Belizn goes above and beyond, ensuring that these best practices are known and used at the community level.
As an international expert, Belizn's innovation and rigorous research from basic science to implementation has had a profound impact on global health and motivated researchers' careers and actions worldwide over the last five decades. His work has sparked and will continue to lead to important developments in this sector as he demonstrates the importance of representation from low- and middle-income countries in global health research.
2023 Canada Gairdner Momentum Award
The 2023 Canada Gairdner Momentum Award laureates are mid-career investigators recognized for exceptional scientific research contributions with continued potential for impact on human health.
Christopher Mushquash, Ph.D., C.Psych
Professor, Department of Psychology, Lakehead University; Psychologist, Dilico Anishinabek Family Care; Vice President Research, Thunder Bay Regional Health Sciences Centre; Chief Scientist, Thunder Bay Regional Health Research Institute
Awarded "For Indigenous-led mental health and substance use research that leads to culturally and contextually appropriate services for Indigenous children, adolescents, and adults."
The Work:
Dr. Christopher Mushquash brings together his clinical experience as a psychologist and his community-based participatory approach to research to meet community needs and improve systems and services that make a difference in people's lives. His innovative work focuses on Indigenous mental health and substance use through evidence-based practices that align with First Nations values. This approach ensures his research and its outcomes are culturally and contextually appropriate for people in First Nations, as well as those in rural and northern communities. Through large team collaborations and partnerships with communities, government and academia, Dr. Mushquash addresses various aspects of mental health for Indigenous communities, such as mental health, substance use, trauma, and general mental wellness. The overarching goals of his research are rooted in the four interconnected directions and include identifying culturally and contextually appropriate targets of intervention, developing methods of measuring community outcomes; developing and testing of interventions that incorporate culture-based knowledge with scientific methods; and the sharing of knowledge among Indigenous and academic communities, clinicians, and policymakers. These themes come together to form a holistic framework to improve not only systems and services but also research involving Indigenous communities. By putting the communities at the forefront of his work, Dr. Mushquash demonstrates the importance of understanding unique contexts and issues experienced by individuals in Indigenous communities. He has effectively shifted the relationship between communities and researchers, enabling more meaningful and relevant research and advancing the understanding of mental health in Indigenous communities. Systems and services are thus better equipped to address the needs of Indigenous, rural and northern communities in a culturally- and contextually-appropriate manner.
The Impact:
Dr. Mushquash champions culturally and contextually appropriate mental health and substance use services for Indigenous communities. His high-calibre work has improved the lives of many Indigenous communities and influenced national mental health and addiction understandings as he brings together western and Indigenous methodologies. His team conducted the first Canadian study of adverse childhood experiences in First Nations adults seeking residential treatment for substance use difficulties. The outcomes enhanced the understanding of the nature of developmental and intergenerational trauma in First Nations people and improved clinical care for those with substance use difficulties. His research has also upended conventional understandingsof mental health in Indigenous families and established best practices for engaging Indigenous people in research. Furthermore, his research has directly influenced federal funding policy in remote First Nations communities. As a leader in his field, Dr. Mushquash has advanced mental health across Canada, garnering various awards, honours and appointments in recognition of his research and clinical expertise. His devotion to the profession and Indigenous mental health can be seen in the impact of his work in changing Canadian policy, educating professionals working with First Nations people, and, more importantly, bettering the quality of life and care of many Indigenous youth and communities.
Gelareh Zadeh, MD, PhD, FRCS(C), FAANS
Professor and Neurosurgery Division Chair, Dan Family Chair in Neurosurgery, Wilkins Family Chair in Brain Tumor Research, Department of Surgery, Temerty Faculty of Medicine, University of Toronto; Head, Division of Neurosurgery, Toronto Western Hospital, Sprott Department of Surgery, University Health Network; Co-Director, Krembil Brain Institute, University Health Network; Senior Scientist, Princess Margaret Cancer Centre, University Health Network
Awarded "For advancing the molecular and genomic understanding of brain tumours, leading to better ways of discriminating, classifying and managing brain tumour subtypes with potential to transform the clinical care of the disease."
The Work:
Dr. Gelareh Zadeh is a neurosurgeon and senior scientist who combines her in-depth clinical knowledge of brain cancer with clinical and translational research to improve the diagnosis and management of adult brain tumours. Dr. Zadeh's research program applies advanced genomic and epigenomic profiling to further our understanding of the molecular regulators of brain tumours and to develop tools that can refine biomarkers of diagnosis to predict treatment responses and ultimately, improve patient outcomes.
Dr. Zadeh's research focuses on advancing knowledge of brain tumours through integration of multiple platforms of genomic analysis. This includes her research incorporating the largest-ever data analysis of meningiomasthe most common type of brain tumour, which has limited treatment options. She co-founded and leads the International Consortium on Meningiomas (ICOM), which provides researchers around the world with access to meningioma samples and data sets, as well as research expertise and collaborations. ICOM also helps to raise awareness of the importance of research funding into this disease. Dr. Zadeh's discoveries in this field have led to new classification criteria that are biologically and clinically relevant, with the potential to outperform the current standard classification system developed by the World Health Organization. Specifically, her research has shown that meningiomas can be classified into four molecular groups, which reveals biological insights into how the cancer behaves. Using molecular features that reflect tumour behavior, the new classification criteria more accurately predicts cancer recurrence. Dr. Zadeh's lab has also produced a comprehensive body of work on neuronal tumours, including schwannomas and peripheral nerve tumours. By performing the first integrated molecular analysis of schwannomas, her group established the genomic and epigenomic road map for sporadic and neurofibromatosis type 2 (NF2)-related schwannomas and identified a novel fusion protein that can be used for diagnostic, prognostic and therapeutic benefit. Similarly, Dr. Zadeh's research has shown that the transformation of benign neuronal tumours to malignant cancers occurs via two independent molecular pathways, both of which can be therapeutically targeted. Another key contribution of her work has demonstrated the utility of plasma-based biomarkers for diagnosis, discrimination and determination of response to treatment, for a wide variety of brain tumours.
The Impact:
Dr. Zadeh exemplifies an extraordinary commitment to advancing our understanding of brain tumour biology to improve patient outcomes. Her team has made significant strides in understanding how molecular features influence tumour management and has identified novel approaches to reduce the negative side effects of brain tumour treatments. Additionally, her team has identified plasma biomarkers that can help to diagnose intracranial tumours, predict treatment response and detect early recurrence, as well as potential drugs to treat malignant brain tumours. Her work is having a considerable impact in the diagnosis and clinical management of brain tumours and is giving hope to individuals affected by brain cancer.
About the Gairdner Foundation:
The Gairdner Foundation, established in 1957, is dedicated to fulfilling James A. Gairdner's vision to recognize major research contributions to the treatment of disease and alleviation of human suffering. Through annual prestigious Canada Gairdner Awards, the Gairdner Foundation celebrates the world's most creative and accomplished researchers whose work is improving the health and wellbeing of people around the world. Since its inception, 410 awards have been bestowed on laureates from over 40 countries, and of those awardees, 96 have gone on to receive Nobel Prizes.
The Gairdner Foundation believes in coming together to openly discuss science to better engage the public, understand the problems we face, and work together to find solutions. Since its founding, a number of outreach events and programs have been developed with the goal of inspiring the next generation of scientific innovators and fostering an informed society.
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2023 CANADA GAIRDNER AWARDS RECOGNIZE WORLD-RENOWNED SCIENTISTS FOR TRANSFORMATIVE CONTRIBUTIONS TO RESEARCH IMPACTING HUMAN HEALTH - Yahoo Finance
Edmonton AI guru Rich Sutton has lost his DeepMind but not his ambition – National Post
This is a new conversation series by Donna Kennedy-Glans, a writer and former Alberta cabinet minister, featuring newsmakers and intriguing personalities. This week: AI rock star Rich Sutton.
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What should one make of Rich Sutton? Hes a rock star in AI (artificial intelligence), and a geek to meet.
In 2017, he partnered with Googles DeepMind project, opening its first ever international AI research office in Edmonton, in collaboration with the University of Alberta.
AI machine learning occupies a lot of bandwidth in the news cycle. With all the hype, its easy to overlook Googles late January decision to shutter Edmontons DeepMind lab. In the midst of a heightened AI race, why would Google put the brakes on pioneering research at an Alberta lab?
Its been a tough couple of months for Rich Sutton. He also lost his father. But when we connect for conversation, I find him remarkably sanguine in his black-and-white plaid flannel shirt, trim grey beard, earbuds and hair thats long enough to be worn in a ponytail.
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Rich looks every bit the quintessential researcher. A guy who has devoted his life to figuring out ways to teach a machine to learn, through trial and error. Thats his specialty reinforcement learning.
A Canadian citizen since 2015, with his expertise, the erstwhile American is a hot commodity and could work anywhere.
Are you staying in Alberta? I ask.
Thats the plan at present, he answers, then confidently declares, Im going to find a way for it to continue to be really good without DeepMind.
And what does this pioneer of reinforcement learning have in mind?
Im going to make a non-profit research organization, for pure research, and well be funded by donors and corporations that are interested in seeing the research done rather than making money out of it. And because of that, it will be entirely open and there will be no need to hide, or to patent things.
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This sounds familiar. OpenAI, co-founded by Elon Musk as a non-profit in 2015, pledged to advance technology for the benefit of humanity. In 2019, the company changed course to allow big investors, including Microsoft, to chase corporate profit.
This sounds like a Canadian edition of OpenAI, I suggest. Rich agrees: That is actually a pretty good way to think about it. Open AI as it used to be. Open AI when it was non-profit, before it became commercial.
Rich hasnt pitched the idea to Elon Musk, yet. He knows he needs to find like-minded champions of Big Science; people interested in doing the research needed to create the future.
His tone is even, but he doesnt quite hide his frustration with Big Techs emphasis on commercial applications of AI research. Whatever the reasons for the decision (to exit the research lab in Edmonton), the effect of the decision will be to shift the emphasis within DeepMind less toward reinforcement learning and more toward things like large language models, Rich explains. He adds: And that is unfortunate, I think. Thats going to be seen as a mistake in the long run.
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Then he qualifies his point: But who am I? I dont have the conceit of claiming that I know what business decisions should be made or what political decisions should be made. Those are for other people. I just know what I should do. I want to work on the prize: Understanding intelligence.
In 2003, Rich was invited to come to the University of Alberta. It was a time of AI Winter in the United States (funding for researchers with ideas like Richs had dribbled to a trickle). Rich was in remission from cancer at the time, and politics cinched his decision to move. George Bush was invading other countries without reason, he said.
I want to believe that Rich can gather a team to stay in Edmonton and build out his vision.
They say that Edmonton is sticky, Rich observes, That somehow people end up wanting to stay, and we dont understand it because it is cold. But its a good place to grow up. It has a good feeling to it. People pull together.
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Given the fear, distrust, and public uncertainty about the implications of artificial intelligence technology Im reminded of the emotions provoked by stem cell research I also wonder if Rich has the chutzpah to pull off an Alberta-based OpenAI.
He is uniquely suited for the task. He checks off all the academic boxes. Hes a known known in the world of AI. Hes also libertarian and thinks, deeply, about why and how its OK for people to want different things and be unconstrained in their individual choices. And he applies this thinking to AI.
When we make AI, what will their goals be? Will we allow them to have independent goals or will we require their goals to be the goals that we have? This is called the alignment problem. Can AIs be free or should they be tightly controlled? Should people be allowed to be free or should people be tightly controlled? Its the same thing.
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Investing in Rich Suttons vision for Edmonton as an AI centre of excellence ought to be a no brainer: imagine scores of grad-student geeks with their whiteboards and fanciful math.
Google and its parent company Alphabet are now digital juggernauts, but less than three decades ago, the search algorithm that revolutionized the internet was mere gobbledegook on a whiteboard. From such beginnings rock stars are born.
Donna Kennedy-Glans is active in the energy business and a multi-generational family farm. Her latest book is Teaching the Dinosaur to Dance: Moving Beyond Business as Usual (2022).
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Edmonton AI guru Rich Sutton has lost his DeepMind but not his ambition - National Post
Online mental health guide created with Indigenous youth in mind – KSTP
Allina Health has teamed up with a local organization to create an online guide for Indigenous and Native Youth struggling with mental health challenges.
Native and Indigenous communities use smudging -the burning of one or more sacred medicines like tobacco, sage, cedar and sweetgrass to cleanse their mind, body and soul.
Its a way that we navigate through life, and we use these medicines as a tool, Nathan Berflund, a Minnesotan, said. It really helps bring you up when youre down.
Jennifer Cortes was one of many students trying to navigate a new normal after the pandemic hit.
It was just a lot and I just fell into a really deep depression from it, Jennifer Cortes, Minnesotan, said.
She said having resources that aligned with her culture turned her life around.
Its one of the reasons why Allina Health launched the Change to Chill web page to make sure Indigenous and Native youth have resources they identify with.
I think the need for more culturally responsive resources is always going to be great. Theres not that same level of visibility or representation, Sydney Hobart, Allina Health community health improvement consultant, said.
Allina Health teamed up with the Indigenous Peoples Task Force to make sure theyre reaching the community through the right channels at a time when youth mental health challenges in the community are getting worse.
The Change to Chill web page lays out resources to cope with anxiety and reduce stress in ways they know best. The youth helped create videos to explain some of the cultural practices and the importance of each method.
It is a big deal. Were very excited about it, Suzanne Nash, Indigenous Peoples Task Force, said. Allina Health is the first medical health center that I know of that has a page just for Indigenous and Native youth and created by the youth.
The group is reviving sacred teachings from their ancestors to promote healing in the present.
Growing up has really changed me and connected me to my culture myself and that is a big way of finding who I am today, Nalia Scheura, a Minnesotan, said.
I think its just a big step toward acknowledging that native people are still here, Cortes said.
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Online mental health guide created with Indigenous youth in mind - KSTP
Opinion | ChatGPT and the Human Mind: How Do They Compare? – The New York Times
To the Editor:
Re Noam Chomsky: The False Promise of ChatGPT, by Noam Chomsky, Ian Roberts and Jeffrey Watumull (Opinion guest essay, nytimes.com, March 8):
Dr. Chomsky and his co-authors are correct that A.I. is nothing like the human mind, which took millions of years to evolve using the resources of the whole earth. A.I. developed over a few decades using a minuscule fraction of the earths riches.
The human brain is amazingly slow, inaccurate and forgetful. It is incapable of quick high-precision floating-point arithmetic, which solves equations to many decimal places. Computers are millions of times faster, with essentially infallible memory, perfect attention and limitless patience. The computer was a product of the human mind, which is truly wonderful.
Contrary to the writers assertions, there is no doubt that machines will eclipse and replace humans at science, math and engineering within this century. But future A.I. will exploit Bayesian algorithms rather than boring old deep learning like ChatGPT. (Bayesian methods use the minimal amount of training data, promise optimal accuracy and quantify uncertainty, capabilities that deep learning lacks.)
It is hard to imagine that computers would also eclipse humans in terms of evil.
Fred DaumCarlisle, Mass.
To the Editor:
Noam Chomsky and his co-authors have explained from a linguistic perspective the unbridgeable chasm that separates A.I. and chatbots, remarkable products of language analysis and synthesis, from human intelligence and knowledge.
But there is a more fundamental difference than the ones mentioned. The intelligence that chatbots create is an abstraction of mind and knowledge, amputated from the primary human data of bodily feelings and emotions on the one hand, and from sensory-perceptual awareness of the external world on the other.
The only way technology can solve this problem would be to create hybrid humans with implanted robotic connections, a development I shudder to contemplate.
Michael RobbinsAmherst, Mass.The writer is a psychoanalyst, a former professor of clinical psychiatry at Harvard University, and the author of Consciousness, Language and Self.
To the Editor:
In their thoughtful and clarifying article on the new breed of A.I. marvels, Noam Chomsky and his co-authors conclude that we can only laugh or cry at their popularity.
On balance, I fear that tears are in order, followed rapidly by hard work to circumvent the potentially destructive powers of artificial intelligence. The Wests lethal cocktail of judgmentalism, commodification and surveillance could all too conceivably lead to A.I. being employed primarily for the oppression of the individual.
Once that happens, we will be looking to Kafka, Bulgakov and Frost for lessons on how to say one thing but mean entirely another.
Fin KeeganNewport, Ireland
To the Editor:
Its been less than six months since ChatGPT exploded into public awareness. It immediately became controversial. Some would outlaw it. Some embrace it. Others applaud.
ChatGPT is a top-notch new learning tool. It even has the potential to break writers block. Why are schools pushing back? Some fear cheating, as though rectitude were more important than learning.
Consider this. Assign students to have ChatGPT write a paper. Then, ask those students to critique the resulting essay by standards of logic, bias, scholarship, content, style and creative thinking. After that, ask the students to rewrite the paper to overcome the shortcomings that their critique has disclosed.
I cant think of a better way to teach better thinking, better writing and better research than by having human students critique a machine-written essay.
What are we afraid of? Lets have faith in our human species.
Jack CummingCarlsbad, Calif.
To the Editor:
Noam Chomsky and his co-authors are right on target. ChatGPT is fascinating, but the hype is way overblown.
My experiences in two areas of interest could not have been more different. In the data science arena, it performs very well when writing Python programs based on my demands, although it requires some editing.
On the other hand, in my hobby area, history, it produces wildly inaccurate results but delivers them with great confidence. The reasons it does this are provided by the essays writers.
Sorry, kids, I would not count on it to write term papers.
Roger GatesFort Worth
To the Editor:
Re Wellesley Students Vote to Open Admissions to Transgender Men (news article, March 15):
Wellesley students pressuring the college to admit trans men have the issue exactly backward. They fail to make the appropriate distinction between sex and culture.
Sex is a biological category generally assigned at birth (or at some point in utero). Its various components may occasionally be at odds with one another. Gender is a cultural category that reflects how a person lives a life, which may at times be at odds with that persons sex.
Womens colleges are cultural/educational institutions devoted to women. They commonly admit trans women, as well they should. It is not in line with that mission to admit trans men or even those preferring to escape traditional gender categorization altogether.
Judith ShapiroBryn Mawr, Pa.The writer was the president of Barnard College from 1994 to 2008 and is emerita professor of anthropology at Barnard and Bryn Mawr College.
To the Editor:
Excuse After Excuse: Black and Latino Developers Struggle to Expand (Real Estate, March 5) points to lack of capital access as a key reason for the abysmal number of successful Black and Latino developers. This challenge is experienced by people of color across industries.
To fix this, we must reform lendings most consequential step: underwriting. Traditionally, underwriters look unfavorably on factors like smaller down payments and higher debt-to-income ratios that are more prevalent among nonwhite borrowers because of longstanding systemic racism.
There are more fair methods to determine an applicants likelihood and ability to repay. Our Underwriting for Racial Justice working group includes lenders piloting different underwriting approaches, such as evaluating credit histories instead of using hard credit score cutoffs. The result is high-performing and more racially diverse portfolios.
The financial industry has an opportunity to replace underwriting standards that perpetuate the crisis of representation in the development industry and beyond. We can spread more equitable practices to make real, systemic change.
Erin Kilmer NeelOakland, Calif.The writer is executive director of Beneficial State Foundation, which seeks a more equitable banking system.
To the Editor:
How Tech Tips the Scales on Gratuities (Business, March 2) shines a bright light on a systemic issue reflecting how this country values its workers. Rather than use tech to guilt customers into tipping, we should pay all workers a living wage thats baked into the cost of goods and services, as it is in so many other nations.
Tom SalyersTakoma Park, Md.The writer is director of communications at the Center for Law and Social Policy.
Link:
Opinion | ChatGPT and the Human Mind: How Do They Compare? - The New York Times